GNH USA

Europe — EMA

Kabiven Perifer

GNH USA supplies Kabiven Perifer (amino acids), an amino acid solution for parenteral nutrition in patients unable to receive enteral feeding.

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, the active ingredients in Kabiven Perifer, is a amino acid solution presented as an intravenous solution for intravenous use. It provides essential amino acids for patients who require parenteral nutrition because they cannot receive enteral feeding.

GNH USA supplies Kabiven Perifer as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and clinics worldwide, with quality control, regulatory compliance and reliable cold‑chain logistics for this parenteral nutrition product.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Kabiven Perifer is an amino acid solution used in parenteral nutrition to support protein synthesis and nitrogen balance.

Parenteral nutrition for patients unable to receive enteral feeding: supplies essential amino acids to maintain nitrogen balance and support metabolic needs. Critical illness or postoperative state: provides substrates for protein synthesis and tissue repair during heightened catabolism. Severe malnutrition: delivers a balanced amino acid profile to meet increased metabolic demands.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Adverse reactions may occur with any intravenous amino acid preparation.

Common Side Effects: - Infusion site erythema or pain - Mild hyperglycemia - Electrolyte disturbances (e.g., mild hyperkalemia or hypophosphatemia) - Nausea or vomiting

Serious or Rare Side Effects: - Anaphylactic or severe hypersensitivity reactions - Severe hypernatremia or metabolic acidosis - Significant elevation of blood urea nitrogen indicating renal overload - Pulmonary edema from fluid overload

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When using Kabiven Perifer, clinicians should observe the following precautions.

Assess renal function: adjust volume and monitor nitrogen load in patients with renal impairment. Monitor electrolytes: regularly check serum potassium, phosphate and calcium levels. Check for amino acid allergies: discontinue if hypersensitivity is observed. Use aseptic technique: ensure sterility of the infusion set and solution. Avoid mixing with incompatible solutions: do not combine with calcium‑containing or high‑pH fluids. Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Kabiven Perifer may interact with other intravenous therapies.

Major Interactions (Avoid): - Concurrent high‑dose potassium solutions: risk of hyperkalemia. - Mixing with calcium‑containing solutions: precipitation may occur. - Co‑administration with other nitrogenous waste products (e.g., urea): can increase renal load.

Moderate Interactions (Monitor Closely): - Use with diuretics: may exacerbate electrolyte shifts. - Concurrent insulin therapy: monitor blood glucose closely. - Co‑infusion with parenteral lipid emulsions: observe triglyceride levels.

Frequently asked questions

What is Kabiven Perifer used for?+
Kabiven Perifer is an intravenous amino acid solution used as part of total parenteral nutrition. It supplies essential and non‑essential amino acids to patients who cannot receive enteral feeding, helping to maintain nitrogen balance, support protein synthesis, and meet metabolic needs during critical illness, surgery or severe malnutrition.
How does the amino acid mixture in Kabiven Perifer work?+
The formulation provides a balanced pool of amino acids that are directly available in the bloodstream. These amino acids act as substrates for ribosomal protein synthesis, replenish intracellular stores, and support metabolic pathways that require nitrogen. By delivering them intravenously, the solution bypasses the gastrointestinal tract, ensuring rapid and reliable availability for tissue repair and immune function.
What determines the dose of Kabiven Perifer?+
The prescribed dose of Kabiven Perifer is individualized by the treating clinician. Factors such as the patient’s weight, age, renal and hepatic function, overall nitrogen balance, and the total caloric goals of the parenteral regimen are considered. The prescriber calculates the appropriate volume and rate to meet the specific nutritional requirements of each patient.
Is Kabiven Perifer safe to use during pregnancy or breastfeeding?+
Safety data for Kabiven Perifer in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Clinicians must evaluate the clinical situation carefully and follow local regulatory guidance before prescribing this product to pregnant or nursing patients.
How do I order Kabiven Perifer from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity of Kabiven Perifer. GNH USA works with hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details (including cold‑chain handling if needed) and any required import documentation.
How does Kabiven Perifer compare with other parenteral amino acid solutions?+
Kabiven Perifer offers a comprehensive blend of ten essential and non‑essential amino acids in a single sterile IV bag, matching the amino acid profile recommended for adult total parenteral nutrition. Compared with some older formulations that contain fewer amino acids or require multiple bags, Kabiven Perifer simplifies preparation, reduces the risk of incompatibility, and provides a balanced nitrogen source for a broad range of clinical scenarios.
What are the storage requirements for Kabiven Perifer?+
Kabiven Perifer must be stored refrigerated at 2 °C to 8 °C. The solution should be kept in its original container, protected from light, and must not be frozen or shaken. Maintaining the cold chain preserves the stability of the amino acids and prevents microbial growth.
How is Kabiven Perifer administered to patients?+
Kabiven Perifer is administered intravenously as part of a total parenteral nutrition regimen. The sterile solution is infused through a dedicated IV line using an infusion pump or gravity set, following aseptic technique. The rate and total volume are determined by the prescribing clinician based on the patient’s nutritional goals and fluid balance.
What are the most serious risks associated with Kabiven Perifer?+
Serious risks include severe hypersensitivity reactions such as anaphylaxis, marked electrolyte disturbances (e.g., hypernatremia, severe hyperkalemia), significant elevation of blood urea nitrogen indicating renal overload, and fluid overload leading to pulmonary edema. Prompt recognition and management of these events are essential, and patients should be monitored closely during infusion.
Who should not receive Kabiven Perifer?+
Kabiven Perifer should be avoided in patients with known hypersensitivity to any of its amino acid components, those with uncontrolled severe electrolyte imbalances, or individuals with acute renal failure where additional nitrogen load could worsen renal function. It is also contraindicated when compatible infusion solutions cannot be ensured, as precipitation may occur.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Fresenius Kabi Ab
Origin
EU

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