GNH USA

Europe — EMA

Kabiven Perifer

GNH USA supplies Kabiven Perifer (Amino Acid Solution), a nutritional support drug for parenteral nutrition in patients unable to receive adequate enteral

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin

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What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Kabiven Perifer, is an amino acid solution presented as an intravenous solution for parenteral use. It provides essential and non‑essential amino acids to patients who cannot receive adequate enteral nutrition. GNH USA supplies Kabiven Perifer as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

What is Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin used for?

Kabiven Perifer is an amino acid solution used in the context of parenteral nutrition to address protein and metabolic needs. - Inadequate enteral intake: provides essential amino acids to meet nutritional requirements when oral or tube feeding is insufficient. - Post‑operative or trauma care: supplies amino acids to support wound healing and catabolic stress in surgical and trauma patients. - Critical illness: maintains protein balance and metabolic support for critically ill patients receiving peripheral parenteral nutrition.

What are the side effects of Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

Kabiven Perifer may be associated with a range of infusion‑related reactions.

Common Side Effects: - Hyperglycemia: elevated blood glucose levels during infusion. - Electrolyte disturbances: changes in serum potassium, sodium, or calcium. - Infusion site irritation: redness, pain, or phlebitis at the catheter site. - Nausea or vomiting: gastrointestinal discomfort during or after administration. - Mild fever or chills: transient temperature rise. - Headache: occasional mild headache.

Serious or Rare Side Effects: - Anaphylactic reaction: severe allergic response requiring immediate medical attention. - Metabolic acidosis: significant acid‑base imbalance. - Hyperammonemia: elevated ammonia levels, especially in hepatic impairment. - Renal dysfunction: worsening kidney function in susceptible patients. - Thrombophlebitis: clot formation with vein inflammation. - Severe electrolyte imbalance: life‑threatening potassium or calcium shifts.

What precautions apply to Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin?

When using Kabiven Perifer, clinicians should observe several safety measures. - Renal function: monitor patients with impaired kidney function closely. - Electrolyte balance: check serum electrolytes before and during therapy. - Metabolic monitoring: watch for hyperglycemia and acid‑base changes. - Infusion rate: adhere to prescribed rates to avoid fluid overload. - Compatibility: verify compatibility with other intravenous solutions before mixing. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin interact with?

Kabiven Perifer can interact with other intravenous agents and systemic medications.

Major Interactions (Avoid): - Concurrent high‑dose potassium solutions: may cause dangerous hyperkalemia. - Calcium‑containing admixtures: can precipitate and obstruct catheters.

Moderate Interactions (Monitor Closely): - Dextrose‑rich solutions: may exacerbate hyperglycemia. - Loop diuretics: can alter electrolyte homeostasis. - Other parenteral nutrition components: may require dose adjustments to maintain balance.

Frequently asked questions

What is Kabiven Perifer used for?+
Kabiven Perifer is an intravenous amino acid solution used as part of parenteral nutrition. It supplies essential and non‑essential amino acids to patients who cannot meet their protein and metabolic needs through oral or tube feeding, such as those in surgical, trauma, or critical‑care settings.
How does the amino acid mixture in Kabiven Perifer work?+
The solution provides a balanced profile of amino acids that are directly absorbed into the bloodstream. Cells use these building blocks to synthesize proteins, support tissue repair, maintain nitrogen balance, and fulfill the metabolic demands of patients receiving parenteral nutrition.
What is the usual dose of Kabiven Perifer?+
The prescribed dose of Kabiven Perifer is individualized by the treating clinician based on the patient’s weight, nutritional requirements, renal and hepatic function, and overall clinical condition. Healthcare professionals calculate the appropriate volume and infusion rate for each patient.
Is Kabiven Perifer safe during pregnancy or breastfeeding?+
The safety of Kabiven Perifer in pregnancy or lactation has not been definitively established. Use should be considered only if the potential benefit justifies any potential risk to the fetus or infant, and decisions are made by the prescribing physician.
How do I order Kabiven Perifer from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.
How does Kabiven Perifer compare with other parenteral amino acid solutions?+
Kabiven Perifer offers a comprehensive blend of ten amino acids in concentrations designed for peripheral intravenous administration. Compared with some alternatives that may require central line access or have different amino‑acid profiles, Kabiven Perifer is formulated for use through peripheral catheters, providing flexibility in settings where central access is not feasible.
What are the storage and handling requirements for Kabiven Perifer?+
Kabiven Perifer should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the solution in its original packaging until use, and discard any product that appears discolored, cloudy, or has particulate matter.
How is Kabiven Perifer administered?+
The product is administered intravenously, typically through a peripheral vein. It is infused over a prescribed period using an infusion pump or controlled drip set, following the clinician’s recommended rate and total volume to ensure safe delivery of amino acids.
What are the most serious risks associated with Kabiven Perifer?+
Serious risks include anaphylactic reactions, metabolic acidosis, hyperammonemia, severe electrolyte disturbances, and renal dysfunction. Patients should be monitored closely for signs of these events, and immediate medical intervention is required if they occur.
Who should not receive Kabiven Perifer?+
Kabiven Perifer should be avoided in patients with known hypersensitivity to any of its amino acid components, those with severe renal or hepatic impairment where amino‑acid load could be harmful, and individuals for whom peripheral venous access is unsuitable for the required infusion volume.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Route
Intravenous Use
Manufacturer
Fresenius Kabi Norge As
Origin
EU

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