Juliette (Cyproterone Acetate, Ethinylestradiol)

Cyproterone acetate / ethinylestradiol, the active ingredients in Juliette, are a combined oral contraceptive presented as a tablet for oral use. They work by suppressing ovulation and stabilising the endometrium, thereby preventing pregnancy in women of reproductive age.

GNH USA supplies Juliette as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable access to this EU‑approved contraceptive.

Juliette, a combined oral contraceptive, is used to prevent pregnancy by acting on the hormonal regulation of the menstrual cycle.

Contraception: prevention of pregnancy in women of reproductive age. Acne: reduction of androgen‑dependent acne lesions. Hirsutism: decrease in excessive facial or body hair growth.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Headache: tension‑type or migraine‑like pain. - Breast tenderness: swelling or discomfort. - Spotting: irregular breakthrough bleeding. - Weight gain: modest increase in body weight. - Mood changes: irritability or emotional lability.

Serious or Rare Side Effects: - Venous thromboembolism: deep‑vein clot formation. - Pulmonary embolism: blockage of lung arteries. - Stroke or myocardial infarction: cerebrovascular or cardiac events. - Severe liver dysfunction: jaundice or hepatic failure. - Allergic reactions: rash, swelling, or anaphylaxis. - Visual disturbances: sudden loss of vision or blurred sight.

Juliette should be used with caution and under medical supervision. - Pregnancy contraindication: do not use during pregnancy. - Smoking restriction: avoid if over 35 years and a smoker. - Thromboembolic history: contraindicated in patients with prior clotting disorders. - Liver disease: avoid in severe hepatic impairment. - Hypertension: monitor blood pressure regularly. - Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Juliette may interact with several medicines that alter its efficacy or safety.

Major Interactions (Avoid): - Enzyme inducers (e.g., rifampin, carbamazepine): reduce contraceptive effect. - Anticoagulants (e.g., warfarin): may increase clotting risk. - HIV protease inhibitors: can diminish hormonal activity.

Moderate Interactions (Monitor Closely): - Antifungals (e.g., ketoconazole): may increase hormone levels. - Antidepressants (SSRIs): possible alteration of menstrual bleeding. - Anticonvulsants (e.g., phenytoin): may lower contraceptive reliability.