Jonosteril D5

Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calcium Chloride Dihydrate and Glucose, the active ingredients in Jonosteril D5, are an electrolyte solution presented as an intravenous solution for injection use. It provides fluid and electrolyte replacement for patients with hypovolemia, electrolyte imbalance, or those requiring peri‑operative fluid management. GNH USA supplies Jonosteril D5 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Jonosteril D5 is an intravenous electrolyte solution used to restore fluid balance and correct electrolyte disturbances. - Fluid replacement: rehydrates patients with acute volume loss. - Electrolyte imbalance correction: normalises sodium, potassium, calcium and magnesium levels. - Hypovolemia treatment: supports circulatory volume in trauma or surgical settings. - Peri‑operative fluid management: maintains electrolyte homeostasis during surgery.

Jonosteril D5 may cause a range of infusion‑related reactions.

Common Side Effects: - Infusion site irritation or pain. - Mild hypernatremia or hyponatremia. - Transient hyperkalemia. - Slight elevation of serum calcium. - Hyperglycemia in susceptible patients. - Mild headache or nausea.

Serious or Rare Side Effects: - Severe electrolyte disturbances leading to cardiac arrhythmia. - Anaphylactic or severe hypersensitivity reaction. - Pulmonary edema from fluid overload. - Metabolic acidosis. - Acute kidney injury due to rapid shifts in electrolytes. - Thrombophlebitis at the infusion site.

Jonosteril D5 should be administered with careful clinical monitoring. - Assess electrolyte status: obtain baseline serum electrolytes before infusion. - Monitor fluid balance: track input and output to avoid overload. - Adjust dose in renal impairment: reduce volume or concentration as needed. - Use caution in patients with heart failure or hypertension. - Avoid concurrent administration with other high‑electrolyte IV fluids without adjustment. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Jonosteril D5 can interact with other medications that affect electrolyte or fluid balance.

Major Interactions (Avoid): - Concomitant potassium‑sparing diuretics or high‑potassium supplements: risk of severe hyperkalemia. - Calcium channel blockers combined with high calcium loads: may precipitate hypercalcemia.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: monitor renal function and potassium levels. - NSAIDs: may impair renal clearance of electrolytes. - Insulin therapy: glucose content may require insulin dose adjustment. - Other IV fluids: coordinate electrolyte concentrations to prevent overload.