GNH USA

Europe — EMA

Jenamazol

GNH USA supplies Jenamazol (Clotrimazole), an imidazole antifungal for vulvovaginal candidiasis. Request a quote for global supply for hospitals.

Clotrimazole

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1
Pack/s

What is Clotrimazole?

Clotrimazole, the active ingredient in Jenamazol, is an imidazole antifungal presented as a vaginal formulation for vaginal use. It treats vulvovaginal candidiasis, a common yeast infection affecting women.

GNH USA supplies Jenamazol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Clotrimazole used for?

Jenamazol, an imidazole antifungal, is used to manage Candida infections affecting various mucosal and skin sites.

- Vulvovaginal candidiasis: relieves symptoms and eradicates Candida overgrowth in the vagina. - Cutaneous candidiasis: treats superficial skin infections caused by Candida species. - Oropharyngeal candidiasis: helps clear yeast infection of the mouth and throat.

What are the side effects of Clotrimazole?

Common Side Effects: - Local irritation: burning or stinging at the site of application. - Itching: mild pruritus in the vaginal area. - Discharge: increased vaginal secretions. - Dryness: sensation of dryness or tightness. - Redness: mild erythema around the application site. - Odor change: temporary alteration of vaginal odor.

Serious or Rare Side Effects: - Allergic reaction: hives, swelling, or difficulty breathing. - Severe skin rash: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Liver toxicity: rare signs of hepatitis such as jaundice. - Systemic hypersensitivity: fever, chills, or malaise. - Persistent vaginal ulceration. - Unexplained bleeding or severe irritation.

What precautions apply to Clotrimazole?

Before using Jenamazol, consider the following safety measures. - Pregnancy: consult a healthcare professional before use. - Breastfeeding: discuss potential risks with a physician. - Allergy: avoid if known hypersensitivity to clotrimazole or other imidazoles. - Concurrent vaginal products: do not use with other intravaginal medications unless directed. - Immunocompromised patients: monitor closely for treatment failure. - Store at room temperature: keep in the original packaging, protect from moisture and heat.

What does Clotrimazole interact with?

Clotrimazole may interact with other medicines; review the following categories.

Major Interactions (Avoid): - Systemic azole antifungals: increased risk of additive toxicity. - Warfarin: potential enhancement of anticoagulant effect.

Moderate Interactions (Monitor Closely): - Oral contraceptives: possible reduction in hormonal efficacy. - Topical steroids: may diminish antifungal activity. - Antacids: could affect absorption of concurrently administered oral agents. - Other intravaginal medications: may alter local drug concentration.

Frequently asked questions

What is Jenamazol used for?+
Jenamazol contains clotrimazole and is used to treat vulvovaginal candidiasis, a yeast infection of the vagina. It may also be employed for other Candida infections such as skin or oral thrush, depending on the formulation and physician recommendation.
How does clotrimazole work?+
Clotrimazole blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for producing ergosterol, a key component of the fungal cell membrane. This inhibition disrupts membrane integrity, leading to fungal cell death and resolution of the infection.
What is the usual dose of Jenamazol?+
The specific dosing regimen for Jenamazol is determined by the prescribing healthcare professional based on the infection severity, patient characteristics, and local guidelines. Patients should follow the exact instructions provided by their prescriber.
Is Jenamazol safe during pregnancy or breastfeeding?+
Safety data for clotrimazole in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Jenamazol.
How do I order Jenamazol from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Jenamazol compare with other antifungal options?+
Clotrimazole is an imidazole antifungal with a broad spectrum against Candida species. Compared with azole agents like fluconazole, clotrimazole is typically applied locally, offering high concentrations at the infection site with minimal systemic exposure, which can reduce systemic side‑effects.
How should Jenamazol be stored and handled?+
Store Jenamazol at room temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight, and excessive heat to maintain product stability and efficacy.
How is Jenamazol administered?+
Jenamazol is intended for vaginal use. The prescribed tablet or suppository is inserted into the vagina according to the prescriber’s instructions, usually once daily for a specified number of days, and should not be used orally or intravenously.
What are the most serious risks associated with Jenamazol?+
Serious adverse reactions, although rare, include severe allergic responses such as anaphylaxis, Stevens‑Johnson syndrome, toxic epidermal necrolysis, and significant liver toxicity. Patients should seek immediate medical attention if they experience symptoms like difficulty breathing, widespread rash, or jaundice.
Who should not use Jenamazol?+
Individuals with a known hypersensitivity to clotrimazole, other imidazole antifungals, or any component of the formulation should avoid using Jenamazol. Additionally, patients with severe liver disease or those taking interacting medications listed under major interactions should consult their clinician before use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Clotrimazole
Route
Vaginal Use
Manufacturer
Quintesence S.R.O.
Origin
EU

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