Jeanine

Dienogest/Ethinylestradiol, the active ingredient in Jeanine, is a combined oral contraceptive presented as an oral tablet for oral use. It prevents pregnancy in women of reproductive age.

GNH USA supplies Jeanine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Jeanine, a combined oral contraceptive, is indicated for hormonal contraception.

- Prevention of pregnancy: provides reliable contraceptive protection for women of child‑bearing potential. - Menstrual cycle regulation: helps achieve more predictable monthly bleeding patterns. - Acne management: may improve hormonal acne associated with menstrual fluctuations. - Endometriosis symptom control: reduces menstrual pain and lesion progression in some patients.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Breast tenderness: temporary swelling or discomfort. - Headache: occasional tension‑type headaches. - Weight gain: modest increase in body weight. - Mood changes: fluctuations in mood or irritability. - Spotting: irregular light bleeding between periods.

Serious or Rare Side Effects: - Deep vein thrombosis: blood clot formation in deep veins. - Pulmonary embolism: clot migration to lung arteries. - Stroke: cerebrovascular accident due to clot. - Myocardial infarction: heart attack risk. - Severe allergic reaction: rash, swelling, difficulty breathing. - Liver dysfunction: jaundice or abnormal liver enzymes.

Before prescribing Jeanine, clinicians should assess individual risk factors and counsel patients on safe use. - Thrombotic risk assessment: evaluate personal or family history of clotting disorders. - Blood pressure monitoring: screen for hypertension before initiation. - Smoking status: avoid use in women over 35 who smoke. - Liver function evaluation: consider hepatic impairment before prescribing. - Pregnancy avoidance: ensure patient is not pregnant and advise effective backup methods. - Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Jeanine may interact with several medicines that affect hormone metabolism or increase clot risk.

Major Interactions (Avoid): - Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin): reduce contraceptive efficacy. - Rifampicin and other strong CYP3A4 inducers: markedly lower hormone levels. - St. John’s wort: herbal inducer that may compromise contraceptive protection.

Moderate Interactions (Monitor Closely): - Certain antibiotics (e.g., tetracycline, metronidazole): may slightly reduce effectiveness. - Antifungal agents (e.g., ketoconazole, itraconazole): can increase hormone concentrations. - Antiretroviral protease inhibitors: may alter plasma levels, requiring clinical monitoring.