GNH USA

Europe — EMA

Izinova

GNH USA supplies Izinova (magnesium sulfate, sodium sulfate, potassium sulfate), a mineral supplement for electrolyte replenishment and constipation relief.

Magnesium Sulfate Heptahydrate, Sodium Sulfate Anhydrous, Potassium Sulphate

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What is Magnesium Sulfate Heptahydrate, Sodium Sulfate Anhydrous, Potassium Sulphate?

Magnesium sulfate, sodium sulfate, potassium sulfate, the active ingredient in Izinova, is a mineral supplement presented as an oral formulation for oral use. It helps restore electrolyte balance and may be used in conditions requiring mineral supplementation.

GNH USA supplies Izinova as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Magnesium Sulfate Heptahydrate, Sodium Sulfate Anhydrous, Potassium Sulphate used for?

Izinova provides mineral salts that support electrolyte homeostasis and osmotic activity in the gastrointestinal tract.

- Electrolyte replenishment: restores magnesium, sodium and potassium levels in patients with deficiency or loss due to illness or treatment. - Constipation relief: the osmotic action of sulfate salts draws water into the bowel, facilitating stool passage. - Prevention of hypomagnesemia: supplies magnesium to reduce risk of muscle cramps and cardiac arrhythmias in at‑risk individuals.

What are the side effects of Magnesium Sulfate Heptahydrate, Sodium Sulfate Anhydrous, Potassium Sulphate?

Izinova may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Nausea: mild stomach upset after ingestion. - Abdominal cramping: discomfort due to osmotic activity. - Diarrhea: loose stools from increased intestinal water. - Headache: occasional mild headache. - Dizziness: transient light‑headedness. - Metallic taste: brief aftertaste.

Serious or Rare Side Effects: - Hypermagnesemia: elevated magnesium levels causing muscle weakness or cardiac effects. - Hyperkalemia: excess potassium leading to arrhythmias. - Severe electrolyte imbalance: significant shifts in sodium or potassium. - Anaphylactic reaction: rare allergic response with rash, swelling, or breathing difficulty. - Severe hypotension: marked drop in blood pressure. - Acute renal failure: in patients with pre‑existing kidney disease.

What precautions apply to Magnesium Sulfate Heptahydrate, Sodium Sulfate Anhydrous, Potassium Sulphate?

When considering Izinova, clinicians should evaluate patient-specific factors and monitor for safety. - Assess baseline electrolyte levels: ensure magnesium, sodium and potassium are within normal range before initiation. - Monitor renal function: impaired kidneys may reduce clearance of the salts. - Avoid in severe renal impairment: risk of accumulation and toxicity. - Use caution with cardiac conduction disorders: electrolyte shifts can affect rhythm. - Do not combine with other osmotic laxatives: may cause excessive fluid loss. - Store at ambient temperature: keep in the original pack, protect from moisture.

What does Magnesium Sulfate Heptahydrate, Sodium Sulfate Anhydrous, Potassium Sulphate interact with?

Izinova can interact with several medicines that affect electrolyte balance or neuromuscular transmission.

Major Interactions (Avoid): - Neuromuscular blocking agents: potentiates muscle relaxation. - Calcium channel blockers: additive hypotensive effect. - Tetracycline antibiotics: reduced absorption of the antibiotic. - Potassium‑sparing diuretics: risk of hyperkalemia. - ACE inhibitors: may enhance potassium retention.

Moderate Interactions (Monitor Closely): - Loop diuretics: may increase electrolyte loss. - Other mineral supplements: monitor total intake to avoid excess. - Antacids containing aluminum or magnesium: possible additive gastrointestinal effects. - NSAIDs: may affect renal handling of electrolytes. - Oral contraceptives: monitor for altered potassium levels.

Frequently asked questions

What is Izinova used for?+
Izinova is an oral mineral supplement that provides magnesium, sodium and potassium ions. It is used to help restore electrolyte balance, relieve constipation through osmotic action, and prevent deficiencies of these essential minerals in patients who have lost them due to illness, medication or dietary factors.
How does magnesium sulfate, sodium sulfate and potassium sulfate work in Izinova?+
After ingestion, the three salts dissociate into Mg2+, Na+, K+ and sulfate ions. The cations replenish systemic electrolyte pools, supporting muscle, nerve and cardiac function. Sulfate ions act osmotically in the gut, drawing water into the lumen to soften stool and promote bowel movements.
What is the usual dose of Izinova?+
The appropriate dose of Izinova is determined by the prescribing healthcare professional based on the patient’s age, clinical condition, electrolyte status and other medications. Dosage instructions are individualized and should be followed exactly as written on the prescription label.
Is Izinova safe to use during pregnancy or breastfeeding?+
Safety of Izinova in pregnancy or while breastfeeding has not been fully established. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.
How do I order Izinova from GNH USA?+
To order Izinova, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Izinova compare with other electrolyte supplements?+
Izinova combines three mineral salts—magnesium, sodium and potassium—in a single oral formulation, offering a broader electrolyte profile than single‑ion supplements. This can simplify dosing for patients who need multiple electrolytes, whereas other products may provide only one or two of these ions.
What are the storage and handling requirements for Izinova?+
Izinova should be stored at ambient temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.
How is Izinova administered?+
Izinova is taken orally, usually with a full glass of water. It may be taken with or without food, depending on the prescriber’s recommendation. Swallow the tablet or capsule whole; do not crush or chew unless instructed otherwise.
What are the most serious risks associated with Izinova?+
Serious risks include hypermagnesemia, hyperkalemia, severe electrolyte imbalance, anaphylactic reactions and acute renal failure in patients with compromised kidney function. Prompt medical attention is required if symptoms such as muscle weakness, irregular heartbeat, severe dizziness or allergic signs appear.
Who should not use Izinova?+
Izinova should be avoided in individuals with severe renal impairment, known hypersensitivity to any of its components, uncontrolled cardiac conduction disorders, or those already receiving high doses of the same mineral salts without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Magnesium Sulfate Heptahydrate, Sodium Sulfate Anhydrous, Potassium Sulphate
Route
Oral Use
Manufacturer
Mayoly Pharmaceuticals Italia S.R.L.
Origin
EU

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