Ivor

Bemiparin Sodium, the active ingredient in Ivor, is a low molecular weight heparin presented as a subcutaneous solution for injection use. It is employed to prevent and treat venous thromboembolic disorders in adult patients, including those undergoing surgery or at risk of deep‑vein thrombosis.

GNH USA supplies Ivor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies, clinics and other healthcare facilities worldwide, ensuring consistent quality and regulatory compliance.

Bemiparin Sodium is used in the prevention and treatment of venous thromboembolism.

- Deep vein thrombosis (DVT) prophylaxis: reduces the risk of clot formation in patients undergoing surgery or immobilisation. - Pulmonary embolism treatment: helps dissolve existing clots and prevents new ones in acute cases. - Post‑operative thrombosis prevention: lowers incidence of venous clots after orthopedic or abdominal surgery. - Acute coronary syndrome adjunct: provides anticoagulation support when combined with antiplatelet therapy.

Bemiparin Sodium may be associated with a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Injection site pain or erythema: mild discomfort at the subcutaneous site. - Bruising or hematoma: localized bleeding under the skin. - Minor bleeding: such as gum or nosebleeds.

Serious or Rare Side Effects: - Major hemorrhage: life‑threatening internal bleeding. - Heparin‑induced thrombocytopenia (HIT): immune‑mediated platelet drop. - Spinal or epidural hematoma: bleeding in the spinal canal after neuraxial procedures.

When using Bemiparin Sodium, several precautions should be observed to minimise risk. - Renal impairment: dose adjustment or close monitoring may be required. - History of bleeding: assess risk‑benefit before initiating therapy. - Concomitant anticoagulants: avoid combined use unless specifically directed. - Antiplatelet therapy: monitor for increased bleeding when used together. - Surgical procedures: discontinue before invasive surgery as advised. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Bemiparin Sodium can interact with other medicines, affecting its anticoagulant effect.

Major Interactions (Avoid): - Concurrent use with other anticoagulants (e.g., warfarin, direct oral anticoagulants): markedly increased bleeding risk. - Combination with antiplatelet agents (aspirin, clopidogrel): heightened hemorrhagic potential. - Use with fibrinolytic therapy (e.g., alteplase): severe bleeding complications.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory drugs (NSAIDs): may augment bleeding tendency. - Selective serotonin reuptake inhibitors (SSRIs) or SNRIs: can increase risk of gastrointestinal bleeding. - Herbal supplements containing ginkgo, garlic or ginger: potential additive anticoagulant effect.