GNH USA

Europe — EMA

Ivabradín Teva Slovakia

GNH USA supplies Ivabradín Teva Slovakia (Ivabradine), an If channel inhibitor for chronic stable angina and heart failure with reduced ejection fraction.

Ivabradine

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What is Ivabradine?

Ivabradine, the active ingredient in Ivabradín Teva Slovakia, is an If channel inhibitor presented as an oral dosage form for oral use. It is used to lower heart rate in patients with chronic stable angina pectoris and in heart failure with reduced ejection fraction.

GNH USA supplies Ivabradín Teva Slovakia as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ivabradine used for?

Ivabradine is used to manage cardiac conditions that benefit from selective heart‑rate reduction.

Chronic stable angina pectoris: reduces the frequency of angina attacks and improves exercise tolerance. Heart failure with reduced ejection fraction: lowers resting heart rate, helping to alleviate symptoms and decrease hospitalization risk. Elevated resting heart rate in coronary artery disease: helps control heart rate when beta‑blockers are not tolerated.

What are the side effects of Ivabradine?

Adverse reactions may occur with ivabradine therapy.

Common Side Effects: - Visual disturbances (phosphenes) - Headache - Dizziness - Fatigue - Nausea

Serious or Rare Side Effects: - Severe bradycardia - Atrial fibrillation - Symptomatic hypotension - Visual loss - Elevated liver enzymes

What precautions apply to Ivabradine?

Use ivabradine with careful clinical monitoring.

Monitor heart rate: ensure resting heart rate remains above the recommended minimum. Avoid in severe hepatic impairment: reduced metabolism may increase exposure. Caution with sick‑sinus syndrome: risk of excessive bradycardia. Do not combine with other strong heart‑rate‑lowering agents without supervision. Store below 25°C: keep in the original pack, protect from moisture.

What does Ivabradine interact with?

Ivabradine may interact with several medicines.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin) - Concomitant use with other heart‑rate‑lowering drugs (beta‑blockers, digoxin) - Calcium‑channel blockers that inhibit CYP3A4 (verapamil, diltiazem)

Moderate Interactions (Monitor Closely): - Moderate CYP3A4 inhibitors (fluconazole, erythromycin) - CYP3A4 inducers (rifampicin, carbamazepine) may reduce efficacy - Antacids or agents that alter gastric pH may affect absorption

Frequently asked questions

What conditions is Ivabradín Teva Slovakia used for?+
Ivabradín Teva Slovakia contains ivabradine, which is prescribed to lower heart rate in patients with chronic stable angina pectoris and in those with heart failure with reduced ejection fraction. It may also be considered when controlling an elevated resting heart rate in coronary artery disease.
How does ivabradine work to lower heart rate?+
Ivabradine selectively blocks the funny (If) current in the sinoatrial node, the heart’s natural pacemaker. By inhibiting this current, the drug slows the spontaneous depolarisation of pacemaker cells, reducing the heart rate without affecting the strength of cardiac contraction.
What is the usual dose of Ivabradín Teva Slovakia?+
The specific dose of Ivabradín Teva Slovakia is determined by the prescribing clinician based on the patient’s clinical condition, heart‑rate response, and tolerance. Dosage adjustments are made according to individual therapeutic goals and safety monitoring.
Is ivabradine safe during pregnancy or breastfeeding?+
The safety of ivabradine in pregnancy and lactation has not been established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by the treating physician.
How do I order Ivabradín Teva Slovakia from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com indicating the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does ivabradine compare with beta‑blockers?+
Both ivabradine and beta‑blockers lower heart rate, but ivabradine does so by selectively inhibiting the If current without affecting myocardial contractility or blood pressure. Beta‑blockers act on adrenergic receptors and have broader cardiovascular effects, which may be advantageous or limiting depending on the patient’s profile.
What are the recommended storage conditions for Ivabradín Teva Slovakia?+
Ivabradín Teva Slovakia should be stored below 25 °C in its original packaging, protected from moisture and direct sunlight. Do not store in a bathroom or near heat sources, and keep the container tightly closed when not in use.
How is Ivabradín Teva Slovakia administered?+
The medication is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with a glass of water and not crushed or chewed unless otherwise instructed.
What are the most serious risks associated with ivabradine?+
The most serious risks include severe bradycardia, atrial fibrillation, symptomatic hypotension, and rare visual disturbances that may affect vision. Patients should be monitored for these events, especially during dose initiation and titration.
Who should not use ivabradine?+
Ivabradine is contraindicated in patients with acute decompensated heart failure, severe hypotension, sick‑sinus syndrome, sinoatrial block, or those taking strong CYP3A4 inhibitors. It should also be avoided in individuals with known hypersensitivity to ivabradine or any of its excipients.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Ivabradine
Route
Oral Use
Manufacturer
Teva Pharmaceuticals Slovakia S.R.O
Origin
EU

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