Itzenal Sugar-Free

Alimemazine Tartrate, the active ingredient in Itzenal Sugar-Free, is a first‑generation H1 antihistamine belonging to the phenothiazine class, presented as an oral tablet for oral administration. It is indicated for the relief of allergic rhinitis, management of urticaria and pruritic skin conditions, and for use as a pre‑operative sedative and anti‑emetic in adult patients.

GNH USA supplies Itzenal Sugar-Free as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across global markets.

Alimemazine Tartrate is used to manage allergic and hypersensitivity conditions by blocking H1 histamine receptors. - Allergic rhinitis: reduces nasal congestion, itching and sneezing. - Urticaria: alleviates hives and associated itching. - Pre‑operative sedation: provides calming effect and helps prevent nausea and vomiting before surgery.

Alimemazine Tartrate may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Drowsiness: feeling of sleepiness or reduced alertness. - Dry mouth: decreased salivation leading to a dry sensation. - Constipation: slowed intestinal motility causing difficulty passing stool. - Blurred vision: temporary visual disturbances.

Serious or Rare Side Effects: - Extrapyramidal symptoms: involuntary muscle movements or rigidity. - Cardiac arrhythmia: irregular heart rhythm that may be serious. - Severe allergic reaction: rash, swelling, or difficulty breathing.

When prescribing Alimemazine Tartrate, clinicians should consider several safety precautions to minimize risk. - Assess sedation level: monitor patients for excessive drowsiness, especially when operating machinery. - Evaluate anticholinergic burden: caution in individuals with glaucoma, urinary retention or enlarged prostate. - Review cardiac history: avoid in patients with known arrhythmias or prolonged QT interval. - Use cautiously in the elderly: increased sensitivity to sedative and anticholinergic effects. - Avoid concurrent CNS depressants: limit use with alcohol, opioids or other sedatives. - Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture.

Alimemazine Tartrate can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid): - CNS depressants: combined use with alcohol, opioids or benzodiazepines may cause profound sedation or respiratory depression. - QT‑prolonging agents: co‑administration with drugs such as quinidine or certain antipsychotics can increase risk of cardiac arrhythmia.

Moderate Interactions (Monitor Closely): - Anticholinergic drugs: additive dry mouth, constipation, urinary retention. - MAO inhibitors: may enhance antihistaminic effects and cause hypertensive reactions. - CYP2D6 substrates: Alimemazine may inhibit metabolism, raising levels of drugs like metoprolol.