GNH USA

Europe — EMA

Isteranda

GNH USA supplies Isteranda (Levonorgestrel), a hormonal contraceptive for emergency contraception and pregnancy prevention.

Levonorgestrel

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What is Levonorgestrel?

Levonorgestrel, the active ingredient in Isteranda, is a progestin presented as a unknown/unknown for oral use. It is used for emergency contraception and ongoing pregnancy prevention in women of reproductive age.

GNH USA supplies Isteranda as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Levonorgestrel used for?

Levonorgestrel acts as a hormonal contraceptive to prevent unintended pregnancy.

Emergency contraception: Provides post‑coital protection when taken within the recommended time frame to reduce the risk of pregnancy. Prevention of pregnancy: Used as a regular oral progestin to inhibit ovulation and maintain contraceptive efficacy in women seeking ongoing birth control. Family planning: Supports women in managing fertility as part of a broader contraceptive strategy.

What are the side effects of Levonorgestrel?

Levonorgestrel may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Nausea or abdominal discomfort - Headache or dizziness - Breast tenderness - Irregular menstrual bleeding or spotting - Fatigue or mild mood changes - Lower abdominal cramping

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) - Persistent high blood pressure - Deep vein thrombosis or pulmonary embolism - Severe abdominal pain indicating ectopic pregnancy - Unexplained vaginal bleeding lasting more than two weeks

What precautions apply to Levonorgestrel?

Before using Isteranda, consider the following safety measures. - Contraindications: Do not use if you have a known hypersensitivity to levonorgestrel or any tablet components. - Medical history: Inform your healthcare provider of any history of thromboembolic disorders, liver disease, or hormone‑sensitive cancers. - Drug interactions: Review concomitant medications with a clinician, especially enzyme‑inducing agents. - Pregnancy testing: Verify you are not already pregnant before taking emergency contraception. - Breastfeeding: Discuss potential effects with a healthcare professional if you are nursing. - Store at ambient temperature: Keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.

What does Levonorgestrel interact with?

Levonorgestrel may interact with other medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid): - Rifampicin, carbamazepine, phenytoin, or other strong enzyme inducers that may reduce contraceptive efficacy. - St. John’s wort, a herbal inducer of hepatic metabolism, which can lower levonorgestrel levels.

Moderate Interactions (Monitor Closely): - Antifungal agents such as ketoconazole that may increase plasma concentrations. - Antiretroviral drugs (e.g., protease inhibitors) that can affect hormone metabolism. - Certain antibiotics (e.g., griseofulvin) with potential modest impact on effectiveness.

Frequently asked questions

What is Isteranda used for?+
Isteranda contains levonorgestrel, a progestin used for emergency contraception after unprotected intercourse and as a regular oral method to prevent pregnancy in women of reproductive age.
How does levonorgestrel work in Isteranda?+
Levonorgestrel works by binding to progesterone receptors, suppressing ovulation, thickening cervical mucus to block sperm, and altering the uterine lining to reduce the chance of implantation.
What is the usual dose of Isteranda?+
The specific dose and regimen of Isteranda are determined by the prescribing healthcare professional based on the indication and patient characteristics.
Is Isteranda safe to use during pregnancy or breastfeeding?+
Isteranda is intended to prevent pregnancy and should not be used if you are already pregnant. Its safety during breastfeeding should be discussed with a healthcare provider, as limited data are available.
How do I order Isteranda from GNH USA?+
To order Isteranda, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Isteranda compare with other emergency contraceptives?+
Isteranda’s active ingredient, levonorgestrel, is a widely used progestin offering effective post‑coital contraception when taken within 72 hours. Compared with copper IUDs or ulipristal acetate, levonorgestrel is oral, convenient, and generally well tolerated, though efficacy declines with time after intercourse.
How should I store Isteranda?+
Store Isteranda at ambient temperature, below 25 °C, in its original packaging. Keep it away from moisture, heat and direct sunlight to maintain product stability.
How is Isteranda administered?+
Isteranda is taken orally, usually as a single tablet or as directed by a healthcare professional. It should be swallowed with water and taken as soon as possible after unprotected sex for emergency use.
What are the most serious risks associated with Isteranda?+
Serious risks, though rare, include severe allergic reactions, high blood pressure, deep vein thrombosis, pulmonary embolism, and ectopic pregnancy. Immediate medical attention is required if any of these symptoms occur.
Who should not use Isteranda?+
Isteranda should not be used by individuals with a known allergy to levonorgestrel or tablet excipients, those who are already pregnant, or women with certain medical conditions such as active thromboembolic disease, severe liver dysfunction, or hormone‑sensitive cancers, unless advised otherwise by a clinician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Levonorgestrel
Route
Oral Use
Manufacturer
Sandoz Ltd
Origin
EU

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