GNH USA

Europe — EMA

Isosorbide Mononitrate Flamingo Pharma Uk

GNH USA supplies Isosorbide Mononitrate Flamingo Pharma Uk (Isosorbide Mononitrate), an organic nitrate for prevention of angina pectoris and chronic stable

Isosorbide Mononitrate

Request sourcing

1
Pack/s

What is Isosorbide Mononitrate?

Isosorbide Mononitrate, the active ingredient in Isosorbide Mononitrate Flamingo Pharma Uk, is an organic nitrate presented as an oral tablet for oral use. It is employed to prevent angina pectoris and to manage chronic stable angina in adult patients. GNH USA supplies Isosorbide Mononitrate Flamingo Pharma Uk as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Isosorbide Mononitrate used for?

Isosorbide Mononitrate belongs to the organic nitrate class and is used in the management of coronary artery disease. - Prevention of angina pectoris: reduces the frequency and severity of anginal attacks. - Chronic stable angina: improves exercise tolerance and decreases symptom burden. - Stable coronary artery disease: alleviates myocardial ischemia during daily activities.

What are the side effects of Isosorbide Mononitrate?

Common side effects are generally mild and transient.

Common Side Effects: - Headache: often occurs at treatment initiation. - Dizziness or light‑headedness. - Flushing of the face or neck. - Low blood pressure (hypotension). - Nausea or upset stomach. - Palpitations or rapid heartbeat.

Serious or Rare Side Effects: - Severe hypotension leading to syncope. - Acute myocardial infarction. - Life‑threatening allergic reaction (anaphylaxis). - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Significant liver enzyme elevation. - Persistent tachycardia or arrhythmia.

What precautions apply to Isosorbide Mononitrate?

Before initiating therapy, several safety considerations should be reviewed. - Monitor blood pressure: check regularly, especially after dose changes. - Avoid concurrent use with phosphodiesterase‑5 inhibitors: risk of profound hypotension. - Assess renal function: dose may need adjustment in severe impairment. - Use caution in hepatic disease: monitor for drug accumulation. - Store at room temperature: keep in the original container, protect from moisture and light.

What does Isosorbide Mononitrate interact with?

Isosorbide mononitrate can interact with several drug classes, requiring attention to avoid adverse events.

Major Interactions (Avoid): - Sildenafil, tadalafil, and other PDE5 inhibitors: may cause severe hypotension. - Other organic nitrates or nitroglycerin: additive vasodilatory effect. - Potent antihypertensive agents: risk of excessive blood pressure drop.

Moderate Interactions (Monitor Closely): - Diuretics: may enhance hypotensive response. - Beta‑blockers: can further reduce heart rate and blood pressure. - Alcohol: may increase dizziness and hypotension.

Frequently asked questions

What is Isosorbide Mononitrate used for?+
Isosorbide Mononitrate is prescribed to prevent episodes of angina pectoris and to manage chronic stable angina, helping patients with coronary artery disease reduce chest pain during physical activity.
How does Isosorbide Mononitrate work?+
The drug releases nitric oxide after oral absorption, which activates guanylate cyclase in vascular smooth muscle. This raises cyclic GMP levels, causing vasodilation, lowering cardiac preload and afterload, and improving the balance between myocardial oxygen supply and demand.
What is the usual dose of Isosorbide Mononitrate?+
The specific dose and dosing schedule are determined by the prescribing clinician based on the patient’s clinical condition, response, and any concomitant therapies. Patients should follow the prescriber’s instructions exactly.
Is Isosorbide Mononitrate safe during pregnancy or breastfeeding?+
Safety data for use in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any potential risk to the fetus or infant, and this decision must be made by a qualified healthcare professional.
How do I order Isosorbide Mononitrate Flamingo Pharma Uk from GNH USA?+
Enquiries can be submitted via the product page on gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Isosorbide Mononitrate compare with other anti‑anginal drugs?+
Compared with short‑acting nitrates, Isosorbide Mononitrate provides a longer duration of action and more stable plasma concentrations, reducing the need for multiple daily dosing. It differs from beta‑blockers and calcium‑channel blockers, which act through heart‑rate reduction or calcium antagonism rather than direct vasodilation.
What are the storage requirements for Isosorbide Mononitrate?+
Store the product at room temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight, and sources of heat to maintain stability.
How is Isosorbide Mononitrate administered?+
The medication is taken orally, usually with a glass of water. It may be taken with or without food, but patients should follow the specific instructions provided by their healthcare provider.
What are the most serious risks associated with Isosorbide Mononitrate?+
Serious risks include severe hypotension, syncope, myocardial infarction, and rare allergic reactions such as anaphylaxis or severe skin eruptions. Patients should seek immediate medical attention if they experience fainting, chest pain, or signs of an allergic response.
Who should not use Isosorbide Mononitrate?+
Patients with known hypersensitivity to isosorbide mononitrate or other organic nitrates, those with severe hypotension, or individuals taking phosphodiesterase‑5 inhibitors should avoid this medication unless directed otherwise by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Isosorbide Mononitrate
Route
Oral Use
Manufacturer
Flamingo Pharma Uk Ltd
Origin
EU

Related products