GNH USA

Europe — EMA

Isopto-Maxidex

GNH USA supplies Isopto-Maxidex (dexamethasone), a glucocorticoid for ocular inflammation, uveitis and allergic conjunctivitis. Request a quote for supply.

Dexamethasone

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What is Dexamethasone?

Dexamethasone, the active ingredient in Isopto-Maxidex, is a glucocorticoid presented as a 0.1% w/v ophthalmic suspension for ocular use. It reduces inflammation in postoperative eyes, uveitis, allergic conjunctivitis and other inflammatory eye conditions, providing targeted therapy for patients requiring corticosteroid eye drops and is indicated for short‑term management of ocular inflammation to preserve visual function.

GNH USA supplies Isopto-Maxidex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on consistent potency and safety.

What is Dexamethasone used for?

Isopto-Maxidex (dexamethasone) is a glucocorticoid ophthalmic suspension used to manage inflammatory eye conditions. - Post‑operative ocular inflammation: reduces swelling and pain after eye surgery. - Uveitis: controls intra‑ocular inflammation and prevents tissue damage. - Allergic conjunctivitis: alleviates redness, itching and swelling caused by allergens.

What are the side effects of Dexamethasone?

Isopto-Maxidex may cause ocular and systemic adverse reactions, which are categorized by frequency and severity.

Common Side Effects: - Eye irritation: transient burning or stinging after instillation. - Increased intraocular pressure: mild rise detectable on routine exams. - Blurred vision: temporary reduction in visual clarity. - Conjunctival hyperemia: mild redness of the eye.

Serious or Rare Side Effects: - Severe ocular hypertension: significant pressure increase requiring treatment. - Secondary glaucoma: optic nerve damage due to pressure elevation. - Infectious keratitis: corneal infection that may threaten vision. - Hypersensitivity reaction: swelling, rash, or anaphylaxis.

What precautions apply to Dexamethasone?

When prescribing Isopto-Maxidex, clinicians should observe several precautions to minimize risks. - Assess intraocular pressure: baseline measurement before initiating therapy. - Limit duration: use the lowest effective dose for the shortest period. - Monitor for infection: avoid use in active ocular infections unless necessary. - Caution in glaucoma patients: may exacerbate pressure elevation. - Avoid contact lens wear: remove lenses before and after instillation. - Store at room temperature: keep below 25°C, protect from moisture and light in original container.

What does Dexamethasone interact with?

Isopto-Maxidex can interact with other ocular or systemic agents, influencing efficacy or safety.

Major Interactions (Avoid): - Systemic corticosteroids: additive systemic glucocorticoid effects. - Anticholinergic eye drops: may reduce drug absorption. - CYP3A4 inhibitors (e.g., ketoconazole eye drops): increase local dexamethasone levels.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory eye drops: potential additive irritation. - Antiviral eye medications: monitor for reduced antiviral efficacy. - Beta‑blocker eye drops: observe for intraocular pressure changes.

Frequently asked questions

What is Isopto-Maxidex used for?+
Isopto-Maxidex is a dexamethasone ophthalmic suspension indicated for the treatment of postoperative ocular inflammation, uveitis, allergic conjunctivitis and other inflammatory eye conditions where a topical corticosteroid is required to control swelling, pain and redness.
How does dexamethasone work in the eye?+
Dexamethasone penetrates ocular tissues and binds intracellular glucocorticoid receptors. This binding modulates gene transcription, suppresses phospholipase A2, and reduces the synthesis of prostaglandins, leukotrienes and inflammatory cytokines, leading to decreased cellular inflammation and stabilisation of the ocular surface.
What is the usual dose of Isopto-Maxidex?+
The dosing regimen for Isopto-Maxidex is determined by the prescribing clinician based on the specific indication, severity of inflammation and patient response. The prescriber will specify the number of drops, frequency and duration appropriate for each individual case.
Is Isopto-Maxidex safe during pregnancy or breastfeeding?+
Safety data for dexamethasone ophthalmic suspension in pregnancy and lactation are limited, and the product is classified as pregnancy category unknown. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and under medical supervision.
How do I order Isopto-Maxidex from GNH USA?+
To order Isopto-Maxidex, submit an enquiry on the product page at gnh-usa.com, indicating the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Isopto-Maxidex compare with other steroid eye drops?+
Isopto-Maxidex contains dexamethasone, a potent glucocorticoid with a rapid anti‑inflammatory effect. Compared with prednisolone acetate, dexamethasone generally offers a stronger potency per drop, allowing potentially lower dosing frequency, but both share similar safety profiles and require monitoring of intraocular pressure.
How should Isopto-Maxidex be stored and handled?+
Store Isopto-Maxidex at room temperature, below 25 °C, in its original container. Protect the suspension from moisture and direct light. Keep the bottle tightly closed when not in use and discard any product that appears discoloured or contaminated.
How is Isopto-Maxidex administered?+
Instill the prescribed number of drops into the affected eye(s) as directed by the prescriber, typically one to two drops per eye. Avoid touching the tip of the bottle to the eye or any surface. Remove contact lenses before administration and wait several minutes before reinserting them.
What are the most serious risks associated with Isopto-Maxidex?+
Serious risks include severe ocular hypertension or secondary glaucoma, which can lead to optic nerve damage, and rare cases of infectious keratitis or hypersensitivity reactions such as swelling, rash or anaphylaxis. Prompt ophthalmic evaluation is essential if these events occur.
Who should not use Isopto-Maxidex?+
Isopto-Maxidex is contraindicated in patients with known hypersensitivity to dexamethasone or any excipients in the formulation, and it should be avoided in eyes with active viral, fungal or bacterial infections unless the prescriber determines the benefits outweigh the risks.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Dexamethasone
Route
Ocular Use
Manufacturer
Novartis Sverige Ab
Origin
EU

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