GNH USA

Europe — EMA

Isopto-Maxidex

GNH USA supplies Isopto-Maxidex (dexamethasone), a corticosteroid for ocular inflammation, anterior uveitis and allergic conjunctivitis. Request a quote.

Dexamethasone

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What is Dexamethasone?

Dexamethasone, the active ingredient in Isopto-Maxidex, is a corticosteroid presented as a 0.1% w/v ophthalmic suspension for ocular use. It treats post‑operative ocular inflammation, anterior uveitis, allergic conjunctivitis and other inflammatory eye conditions in patients requiring anti‑inflammatory therapy.

GNH USA supplies Isopto-Maxidex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance and regulatory compliance.

What is Dexamethasone used for?

Isopto-Maxidex, a corticosteroid ophthalmic suspension, is used to manage inflammatory eye conditions.

- Post‑operative ocular inflammation: reduces swelling, pain and redness after eye surgery. - Anterior uveitis: controls intra‑ocular inflammation and helps preserve vision. - Allergic conjunctivitis: alleviates itching, redness and watery discharge. - Other inflammatory eye conditions: provides anti‑inflammatory effect in various ocular disorders.

What are the side effects of Dexamethasone?

Ophthalmic dexamethasone may cause local and systemic adverse reactions.

Common Side Effects: - Transient eye irritation: mild burning or stinging on instillation. - Increased intra‑ocular pressure: mild rise detectable on routine exam. - Blurred vision: temporary visual disturbance after dosing. - Conjunctival hyperemia: mild redness of the eye.

Serious or Rare Side Effects: - Secondary ocular infection: risk of bacterial, fungal or viral infection due to immunosuppression. - Cataract formation: accelerated lens opacity with prolonged use. - Severe hypersensitivity: anaphylactic reaction or angioedema.

What precautions apply to Dexamethasone?

When using Isopto-Maxidex, consider the following precautions. - Monitor intra‑ocular pressure: regular eye pressure checks are recommended. - Use with caution in glaucoma patients: may exacerbate pressure elevation. - Avoid in active ocular infections: corticosteroid can worsen infection. - Limit duration of therapy: prolonged use increases risk of cataract and pressure rise. - Pregnancy and lactation: safety not established; prescribe only if benefit outweighs risk. - Store at room temperature: keep below 25°C, protect from moisture and light in original container.

What does Dexamethasone interact with?

Potential drug interactions should be reviewed before initiating therapy.

Major Interactions (Avoid): - Systemic corticosteroids: additive immunosuppression may increase infection risk. - CYP3A4 inhibitors (e.g., ketoconazole): may raise ocular dexamethasone levels.

Moderate Interactions (Monitor Closely): - Anticholinergic eye drops: may reduce tear production, enhancing irritation. - Non‑steroidal anti‑inflammatory eye drops: potential for reduced efficacy. - Antiviral agents (e.g., ganciclovir): monitor for delayed healing.

Frequently asked questions

What is Isopto-Maxidex used for?+
Isopto-Maxidex is an ophthalmic suspension containing dexamethasone that is prescribed to treat post‑operative ocular inflammation, anterior uveitis, allergic conjunctivitis and other inflammatory eye conditions where reduction of swelling, pain and redness is required.
How does dexamethasone work in the eye?+
Dexamethasone acts as a glucocorticoid receptor agonist. After entering ocular cells, it binds to intracellular receptors, alters gene transcription, suppresses pro‑inflammatory cytokines, inhibits phospholipase A2 and reduces leukocyte migration, thereby decreasing inflammation and immune activity within eye tissues.
What is the usual dose of Isopto-Maxidex?+
The dosing regimen for Isopto-Maxidex is determined by the prescribing ophthalmologist based on the specific condition, severity and patient response. The prescriber will specify the number of drops, frequency and duration appropriate for each individual case.
Is Isopto-Maxidex safe during pregnancy or breastfeeding?+
Safety of dexamethasone ophthalmic suspension in pregnancy and lactation has not been established. It should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.
How do I order Isopto-Maxidex from GNH USA?+
To order Isopto-Maxidex, submit an enquiry on the product page at gnh-usa.com, indicating the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Isopto-Maxidex compare with other ocular steroids?+
Isopto-Maxidex delivers dexamethasone, a potent glucocorticoid with a strong anti‑inflammatory profile. Compared with prednisolone acetate or fluorometholone, dexamethasone often provides a faster onset of action but may carry a higher risk of intra‑ocular pressure elevation, requiring careful monitoring.
How should Isopto-Maxidex be stored?+
Store Isopto-Maxidex at room temperature, preferably below 25 °C. Keep the bottle in its original packaging, protect it from moisture and direct light, and ensure the cap is tightly closed to maintain suspension stability.
How is Isopto-Maxidex administered?+
The suspension is applied as eye drops. The patient should wash hands, tilt the head back, pull down the lower eyelid to form a pocket, instill the prescribed number of drops, and close the eye gently for a few seconds. Avoid touching the dropper tip to any surface.
What are the most serious risks associated with Isopto-Maxidex?+
Serious risks include a significant rise in intra‑ocular pressure that can lead to glaucoma, development of cataracts with long‑term use, and secondary ocular infections due to local immunosuppression. Patients should be monitored regularly for these complications.
Who should not use Isopto-Maxidex?+
Isopto-Maxidex is contraindicated in patients with known hypersensitivity to dexamethasone or any formulation component, and it should be avoided in eyes with active viral, fungal or bacterial infections unless directed by a specialist. Caution is also advised for individuals with uncontrolled glaucoma.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Dexamethasone
Route
Ocular Use
Manufacturer
Novartis Norge As
Origin
EU

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