Isomol

Sodium hydrogen carbonate, potassium chloride, sodium chloride and macrogol 3350, the active ingredients in Isomol, are an electrolyte and osmotic laxative preparation presented as an oral solution for oral use. It is used to cleanse the bowel and manage constipation in adults.

GNH USA supplies Isomol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Isomol is employed in gastrointestinal preparation and electrolyte management. - Bowel preparation for colonoscopy: facilitates cleansing of the intestinal tract before endoscopic procedures. - Constipation management: provides osmotic water retention to soften stool and promote bowel movements. - Electrolyte replacement: restores sodium and potassium balance in patients with mild dehydration.

Adverse reactions may occur with oral electrolyte and laxative solutions.

Common Side Effects: - Abdominal bloating: feeling of fullness or distension. - Nausea: mild queasiness during intake. - Flatulence: increased intestinal gas. - Mild electrolyte disturbance: transient changes in serum sodium or potassium. - Thirst: increased desire for fluids. - Headache: occasional mild headache.

Serious or Rare Side Effects: - Severe dehydration: marked fluid loss requiring medical attention. - Significant electrolyte imbalance: hypernatremia or hypokalemia. - Allergic reaction: rash, itching, or angioedema. - Renal impairment: worsening kidney function in susceptible individuals. - Severe abdominal pain: may indicate complications. - Colonic perforation: extremely rare but serious gastrointestinal injury.

Use Isomol with appropriate clinical assessment and monitoring. - Assess renal function: avoid in severe renal impairment. - Monitor electrolytes: check serum sodium and potassium before and during therapy. - Avoid in bowel obstruction: contraindicated when mechanical blockage is present. - Use with caution in elderly: increased risk of dehydration. - Pregnancy and lactation: consult a healthcare professional before use. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Isomol may interact with other medications affecting fluid and electrolyte balance.

Major Interactions (Avoid): - Loop diuretics: may exacerbate electrolyte loss. - Lithium: risk of altered lithium levels. - ACE inhibitors: increased risk of hyperkalemia. - Antacids containing sodium bicarbonate: additive sodium load.

Moderate Interactions (Monitor Closely): - NSAIDs: may affect renal function. - Corticosteroids: increase risk of fluid imbalance. - Oral rehydration solutions: potential overlapping electrolyte content.