Europe — EMA
Isochol
GNH USA supplies Isochol (Hymecromone), a choleretic for biliary disorders, cholestasis and gallstone disease, to support liver function.
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What is Hymecromone?
Hymecromone, the active ingredient in Isochol, is a choleretic presented as an oral dosage form for oral use. It is employed to stimulate bile secretion and flow in patients with biliary disorders, cholestasis, and gallstone disease. GNH USA supplies Isochol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.
What is Hymecromone used for?
Isochol acts as a choleretic agent addressing disorders of bile production and flow. - Biliary disorders: enhances bile output to improve digestion and relieve cholestatic symptoms. - Cholestasis: promotes bile flow, helping to reduce intra‑hepatic bile accumulation. - Gallstone disease: facilitates bile movement, supporting the prevention of stone formation and aiding in symptom management.
What are the side effects of Hymecromone?
Adverse reactions may occur with any medication and should be monitored.
Common Side Effects: - Diarrhea: loose stools occurring during treatment. - Abdominal discomfort: mild pain or cramping in the upper abdomen. - Nausea: feeling of queasiness without vomiting. - Flatulence: increased intestinal gas.
Serious or Rare Side Effects: - Hepatic enzyme elevation: significant rise in liver function tests. - Allergic reaction: rash, itching, or swelling of the face and throat. - Severe abdominal pain: persistent or worsening pain requiring medical evaluation.
What precautions apply to Hymecromone?
Before initiating Isochol, consider the following safety measures. - Liver function monitoring: assess baseline enzymes and repeat as clinically indicated. - Pregnancy and lactation: use only if the potential benefit outweighs potential risk. - Concomitant liver disease: evaluate severity and adjust therapy accordingly. - Drug interactions: review patient medication list for potential interactions. - Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture and direct sunlight.
What does Hymecromone interact with?
Isochol may interact with other agents that affect bile metabolism or hepatic function.
Major Interactions (Avoid): - Cyclosporine: may increase risk of hepatotoxicity. - Rifampicin: can reduce Hymecromone effectiveness by inducing hepatic enzymes.
Moderate Interactions (Monitor Closely): - Oral contraceptives: possible alteration of bile composition. - Statins: monitor liver enzymes for additive hepatic stress. - Antifungal azoles: may affect hepatic metabolism pathways.
Frequently asked questions
What conditions is Isochol used to treat?+
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What is the usual dose of Isochol?+
Is Isochol safe to use during pregnancy or breastfeeding?+
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Product details
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