Iruzid

Hydrochlorothiazide / Lisinopril, the active ingredient in Iruzid, is an ACE inhibitor and thiazide diuretic presented as a combination tablet for oral use. It treats hypertension and edema in adult patients. GNH USA supplies Iruzid as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Iruzid, a combination of an ACE inhibitor and a thiazide diuretic, is used to manage conditions related to elevated blood pressure and fluid retention.

Hypertension: lowers systolic and diastolic blood pressure to reduce cardiovascular risk. Edema: promotes fluid excretion to decrease swelling in peripheral tissues. Cardiovascular risk reduction: helps prevent complications in patients with high‑risk hypertension.

Common Side Effects: - Dizziness or light‑headedness - Persistent dry cough - Increased urination - Electrolyte disturbances such as low potassium

Serious or Rare Side Effects: - Angioedema (swelling of face, lips, tongue) - Severe dehydration or marked electrolyte imbalance - Acute kidney injury or worsening renal function

Before initiating therapy, consider the following precautions: - Blood pressure monitoring: ensure target levels are achieved without excessive drop. - Renal function assessment: check serum creatinine and eGFR regularly. - Electrolyte balance: monitor potassium and sodium levels, especially in patients on other diuretics. - Diabetes management: antihypertensive effect may mask hypoglycaemia symptoms. - Hypersensitivity: discontinue if signs of allergic reaction appear. - Store at ambient temperature: keep in the original container, protect from moisture and light.

Iruzid can interact with several medicines; awareness of the interaction level is essential.

Major Interactions (Avoid): - Aliskiren: combined renin‑angiotensin blockade increases risk of renal impairment. - Potassium‑containing supplements or potassium‑sparing diuretics: may cause dangerous hyperkalaemia. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): can blunt antihypertensive effect and affect renal function.

Moderate Interactions (Monitor Closely): - Lithium: thiazide component may raise lithium levels, requiring dose adjustment. - Other antihypertensives (e.g., beta‑blockers, calcium channel blockers): additive blood‑pressure lowering effect may necessitate careful titration.