GNH USA

Europe — EMA

Irireact

GNH USA supplies Irireact (Pheniramine/Tetryzoline), a antihistamine and alpha‑adrenergic agonist for allergic conjunctivitis, eye itching and redness.

Pheniramine Maleate, Tetryzoline Hydrochloride

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What is Pheniramine Maleate, Tetryzoline Hydrochloride?

Pheniramine maleate / tetryzoline hydrochloride, the active ingredient in Irireact, is an Antihistamine and alpha‑adrenergic agonist presented as eye drops for ocular use. It relieves allergic conjunctivitis, eye itching and redness in adults and children. GNH USA supplies Irireact as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Pheniramine Maleate, Tetryzoline Hydrochloride used for?

Irireact acts on ocular allergic pathways to reduce inflammation and vasodilation. - Allergic conjunctivitis: diminishes itching, tearing and redness caused by allergens. - Eye itching: provides rapid relief of itch sensations in the conjunctiva. - Redness of the eye: constricts conjunctival vessels to lessen visible redness.

What are the side effects of Pheniramine Maleate, Tetryzoline Hydrochloride?

Common Side Effects: - Stinging or burning sensation upon instillation. - Transient blurred vision. - Mild eye irritation or dryness. - Temporary increased redness. - Mild headache. - Slight eye discomfort with contact lens use.

Serious or Rare Side Effects: - Severe ocular irritation or allergic reaction. - Corneal ulceration or keratitis. - Significant increase in intra‑ocular pressure. - Systemic hypersensitivity (rash, swelling). - Anaphylactic reaction. - Persistent visual disturbances.

What precautions apply to Pheniramine Maleate, Tetryzoline Hydrochloride?

Use Irireact only as directed by a qualified eye‑care professional. - Hypersensitivity: avoid if known allergy to pheniramine, tetryzoline or excipients. - Glaucoma: use with caution; monitor intra‑ocular pressure. - Prolonged use: limit to short‑term relief; consult a clinician if symptoms persist beyond 7 days. - Contact lenses: remove lenses before application and wait several minutes before reinserting. - Pediatric use: follow pediatric guidance; avoid in infants unless advised. - Store at room temperature: keep in the original container, protect from light and moisture.

What does Pheniramine Maleate, Tetryzoline Hydrochloride interact with?

Irireact may interact with other medications that affect vascular tone or histamine pathways. Major Interactions (Avoid): - Monoamine oxidase inhibitors (risk of hypertensive episodes). - Systemic decongestants or other ocular vasoconstrictors (excessive vasoconstriction). - Other topical antihistamines (additive ocular irritation). Moderate Interactions (Monitor Closely): - Alcohol (may increase ocular dryness). - Beta‑blocker eye drops (potential additive effect on intra‑ocular pressure). - Multiple antihistamine products (monitor for cumulative sedation or irritation).

Frequently asked questions

What is Irireact used for?+
Irireact is an over‑the‑counter eye‑drop formulation that combines an antihistamine with a vasoconstrictor to relieve symptoms of allergic conjunctivitis, including eye itching, redness, and watery discharge.
How does pheniramine maleate work in Irireact?+
Pheniramine maleate blocks H1 histamine receptors on ocular mast cells, preventing histamine‑induced inflammation and itching. This reduces the allergic response that causes discomfort and tearing.
What is the usual dose of Irireact?+
The dosing regimen for Irireact is determined by the prescribing eye‑care professional. Typically, one or two drops are instilled in the affected eye(s) as needed, but the exact frequency should follow the clinician’s instructions.
Is Irireact safe during pregnancy or breastfeeding?+
Safety data for pheniramine maleate and tetryzoline in pregnancy or lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should consult their healthcare provider before using Irireact.
How do I order Irireact from GNH USA?+
To order Irireact, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Irireact compare with other eye‑drop treatments?+
Irireact combines an antihistamine (pheniramine) with a vasoconstrictor (tetryzoline), offering both anti‑inflammatory and decongestant effects. Alternative products may contain only an antihistamine or only a decongestant, which can be less effective for simultaneous itching and redness.
What are the storage and handling requirements for Irireact?+
Irireact should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from direct sunlight, and avoid moisture to maintain product stability.
How is Irireact administered?+
Irireact is applied topically to the eye. The patient should wash hands, tilt the head back, pull down the lower eyelid, and place the prescribed number of drops into the conjunctival sac. Close the eye gently and avoid blinking excessively.
What are the most serious risks associated with Irireact?+
Serious risks include severe ocular irritation, corneal ulceration, significant rise in intra‑ocular pressure, and systemic allergic reactions such as anaphylaxis. Any sudden worsening of vision or intense pain should prompt immediate medical attention.
Who should not use Irireact?+
Individuals with known hypersensitivity to pheniramine, tetryzoline, or any formulation excipients should avoid Irireact. Patients with uncontrolled glaucoma, severe ocular infections, or those advised against vasoconstrictors by their eye‑care professional should also refrain from use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Pheniramine Maleate, Tetryzoline Hydrochloride
Route
Ocular Use
Manufacturer
Montefarmaco Otc S.P.A.
Origin
EU

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