GNH USA

Europe — EMA

Iremofar

GNH USA supplies Iremofar (Hydroxyzine Hydrochloride), an antihistamine for pruritus and allergic skin reactions. Request a quote for global supply.

Hydroxyzine Hydrochloride

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What is Hydroxyzine Hydrochloride?

Hydroxyzine Hydrochloride, the active ingredient in Iremofar, is an antihistamine presented as a topical formulation for skin application. It works to relieve itching and allergic skin irritation in adults and children when prescribed by a healthcare professional.

GNH USA supplies Iremofar as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Hydroxyzine Hydrochloride used for?

Hydroxyzine Hydrochloride is an antihistamine that acts on skin‑related allergic pathways to reduce itching and inflammation. - Pruritus: provides relief from itching associated with various dermatologic conditions. - Allergic skin reactions: alleviates redness, swelling and discomfort caused by allergic contact dermatitis. - Atopic dermatitis flare‑ups: helps control itch and secondary skin irritation during flare periods.

What are the side effects of Hydroxyzine Hydrochloride?

Hydroxyzine Hydrochloride applied to the skin may cause a range of local and systemic reactions.

Common Side Effects: - Local skin irritation: mild redness or itching at the application site. - Dryness: temporary loss of skin moisture. - Burning sensation: transient warmth or stinging. - Erythema: slight reddening of the skin. - Pruritus worsening: paradoxical increase in itching in rare cases.

Serious or Rare Side Effects: - Allergic contact dermatitis: severe rash, swelling or blistering. - Systemic antihistamine toxicity: drowsiness, dizziness, tachycardia if absorbed in large amounts. - Anaphylaxis: rapid onset of breathing difficulty, swelling of face or throat. - Severe skin necrosis: localized tissue death requiring medical attention. - Hypotension: unusually low blood pressure after extensive absorption.

What precautions apply to Hydroxyzine Hydrochloride?

When using Iremofar, consider the following safety measures. - Pediatric use: apply only under professional supervision and according to prescribed amount. - Broken skin: avoid application on open wounds or severely damaged skin. - Concomitant topical antihistamines: do not layer multiple antihistamine products without guidance. - Glaucoma patients: use with caution due to potential anticholinergic effects. - Pregnancy and lactation: safety not established; consult a healthcare provider before use. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

What does Hydroxyzine Hydrochloride interact with?

Hydroxyzine Hydrochloride may interact with other medicines when absorbed systemically.

Major Interactions (Avoid): - Systemic antihistamines: risk of additive sedation and anticholinergic load. - CNS depressants (e.g., benzodiazepines, opioids): may enhance drowsiness. - Alcohol: can increase sedative effects. - Anticholinergic drugs (e.g., atropine): may intensify anticholinergic side effects. - QT‑prolonging agents: potential for cardiac rhythm disturbances.

Moderate Interactions (Monitor Closely): - Topical corticosteroids: may increase hydroxyzine absorption. - CYP3A4 inhibitors (e.g., erythromycin, ketoconazole): could raise systemic levels if significant skin penetration occurs.

Frequently asked questions

What is Iremofar used for?+
Iremofar contains hydroxyzine hydrochloride and is applied to the skin to relieve itching (pruritus) and reduce irritation from allergic skin reactions such as contact dermatitis. It is intended for short‑term use under the direction of a healthcare professional.
How does hydroxyzine hydrochloride work in Iremofar?+
Hydroxyzine hydrochloride blocks peripheral H1 histamine receptors on skin cells, preventing histamine‑driven nerve activation and inflammation. This reduces the sensation of itch and the redness associated with allergic skin responses.
What is the usual dose of Iremofar?+
The exact amount and frequency of Iremofar application are determined by the prescribing clinician based on the patient’s age, condition severity, and treatment response. Patients should follow the healthcare provider’s instructions precisely.
Is Iremofar safe during pregnancy or breastfeeding?+
Safety data for topical hydroxyzine during pregnancy or lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Iremofar.
How do I order Iremofar from GNH USA?+
To request Iremofar, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Iremofar compare with other antihistamine creams?+
Iremofar’s active ingredient, hydroxyzine hydrochloride, offers both antihistamine and mild sedative properties, which can be advantageous for severe itching. Compared with non‑sedating antihistamine creams, it may provide faster itch relief but may also carry a higher risk of systemic sedation if absorbed.
How should I store Iremofar?+
Store Iremofar at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture, heat and direct sunlight to maintain product stability.
How is Iremofar applied?+
Apply a thin layer of Iremofar to the affected skin area as directed by a healthcare professional, usually 1–2 times daily. Gently rub until the product is absorbed, and wash hands after application to avoid accidental contact with eyes or mucous membranes.
What are the most serious risks associated with Iremofar?+
Serious risks include allergic contact dermatitis, systemic antihistamine toxicity leading to excessive drowsiness or cardiac effects, and rare cases of anaphylaxis. If any severe reaction occurs, discontinue use and seek immediate medical attention.
Who should not use Iremofar?+
Iremofar should not be used by individuals with known hypersensitivity to hydroxyzine or any excipients in the formulation, on severely broken skin, or by patients with conditions that could be worsened by anticholinergic effects, such as uncontrolled glaucoma, without medical advice.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Hydroxyzine Hydrochloride
Route
Cutaneous Use
Manufacturer
Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.
Origin
EU

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