Irbesartan Teva

Irbesartan, the active ingredient in Irbesartan Teva, is a Angiotensin II receptor blocker (ARB) presented as an oral dosage form for oral use. It is employed to manage high blood pressure and to protect kidney function in patients with diabetic nephropathy.

GNH USA supplies Irbesartan Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Irbesartan Teva belongs to the Angiotensin II receptor blocker class and is used to treat conditions related to the renin‑angiotensin system.

- Hypertension: lowers systemic blood pressure and reduces cardiovascular risk. - Diabetic nephropathy: slows the progression of kidney damage in patients with type 2 diabetes.

Irbesartan may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Dizziness: feeling light‑headed, especially after standing. - Headache: mild to moderate pain in the head region. - Fatigue: unusual tiredness or lack of energy.

Serious or Rare Side Effects: - Angioedema: swelling of the face, lips, tongue or throat that may impair breathing. - Severe hypotension: markedly low blood pressure causing fainting. - Acute kidney injury: sudden decline in renal function. - Hyperkalemia: elevated blood potassium that can affect heart rhythm. - Liver enzyme elevation: increased hepatic transaminases indicating liver stress. - Neutropenia: reduced white blood cell count increasing infection risk.

Before initiating therapy with Irbesartan, several safety considerations should be observed.

- Blood pressure monitoring: check regularly to avoid excessive hypotension. - Renal function assessment: evaluate serum creatinine and eGFR before and during treatment. - Serum potassium: monitor for hyperkalemia, especially when combined with potassium‑sparing agents. - Hepatic impairment: use caution in patients with liver disease as metabolism may be altered. - Hypersensitivity: discontinue if signs of allergic reaction such as rash or swelling appear. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Irbesartan can interact with several drug classes, influencing safety or efficacy.

Major Interactions (Avoid): - Aliskiren in diabetic patients: combined use increases risk of renal impairment and hyperkalemia. - Potassium‑sparing diuretics or supplements: may cause dangerous elevations in serum potassium. - ACE inhibitors: concurrent use raises the likelihood of angioedema.

Moderate Interactions (Monitor Closely): - NSAIDs: can blunt antihypertensive effect and affect renal function. - Lithium: may increase lithium concentrations, leading to toxicity. - Cyclosporine: can exacerbate renal dysfunction when used together.