Irbesartan Teva

Irbesartan, the active ingredient in Irbesartan Teva, is a Angiotensin II receptor blocker (ARB) presented as a tablet for oral use. It treats hypertension and diabetic nephropathy in adult patients.

GNH USA supplies Irbesartan Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Irbesartan acts on the renin‑angiotensin‑aldosterone system to control blood pressure and protect kidney function. - Hypertension: lowers systolic and diastolic blood pressure in patients with elevated readings. - Diabetic nephropathy: slows the progression of kidney disease in type 2 diabetes. - Proteinuria in diabetes: reduces urinary protein excretion, contributing to renal protection.

Common Side Effects: - Dizziness: feeling light‑headed, especially after the first dose. - Headache: mild to moderate intensity. - Fatigue: general tiredness without exertion. - Nausea: occasional upset stomach. - Upper respiratory tract infection: mild cold‑like symptoms. - Diarrhea: loose stools.

Serious or Rare Side Effects: - Angioedema: swelling of face, lips, tongue, or throat. - Hyperkalemia: elevated blood potassium levels. - Acute renal impairment: sudden decrease in kidney function. - Hepatic injury: abnormal liver enzymes or jaundice. - Severe hypotension: markedly low blood pressure. - Anaphylactic reaction: rare systemic allergic response.

Before initiating therapy, consider the following precautions: - Blood pressure monitoring: ensure adequate control and avoid excessive drops. - Renal function assessment: check serum creatinine and eGFR regularly. - Serum potassium measurement: monitor for hyperkalemia, especially with concomitant potassium‑sparing agents. - Hepatic impairment: use with caution in patients with severe liver disease. - Pregnancy: avoid use unless clearly needed; discuss risks with a healthcare professional. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Irbesartan may interact with several medicines that affect potassium balance or renal function. Major Interactions (Avoid): - ACE inhibitors: combined use can increase risk of hyperkalemia and renal dysfunction. - Potassium‑sparing diuretics: may cause dangerous elevations in serum potassium. - Aliskiren (in diabetic patients): heightened risk of renal impairment and hyperkalemia. Moderate Interactions (Monitor Closely): - NSAIDs: can reduce antihypertensive effect and impair renal function. - Diuretics (thiazide or loop): may require dose adjustment of Irbesartan. - Lithium: increased lithium levels and potential toxicity. - Rifampin: may lower Irbesartan plasma concentrations, reducing efficacy.