Irbesartan Mylan

Irbesartan, the active ingredient in Irbesartan Mylan, is an angiotensin II receptor blocker (ARB) presented as a tablet for oral use. It is indicated for the treatment of hypertension and for slowing the progression of diabetic nephropathy, helping to control blood pressure and reduce renal stress in adult patients.

GNH USA supplies Irbesartan Mylan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance, regulatory compliance and reliable logistics across multiple regions.

Irbesartan is an angiotensin II receptor blocker used to treat conditions related to the renin‑angiotensin system. - Hypertension: lowers elevated blood pressure and reduces cardiovascular risk. - Diabetic nephropathy: slows kidney function decline in patients with type 2 diabetes. - Proteinuria associated with diabetic kidney disease: decreases urinary protein excretion, supporting renal protection.

Common Side Effects: - Dizziness: sensation of light‑headedness, especially after standing. - Headache: mild to moderate pain in the head region. - Fatigue: feeling unusually tired or weak. - Upper respiratory tract infection: symptoms such as sore throat or nasal congestion. - Nausea: mild stomach discomfort or urge to vomit. - Diarrhea: loose stools occurring intermittently.

Serious or Rare Side Effects: - Angioedema: swelling of the face, lips, tongue, or throat that may compromise breathing. - Hyperkalemia: elevated potassium levels that can affect heart rhythm. - Acute kidney injury: sudden decline in renal function, indicated by rising creatinine. - Hepatic injury: abnormal liver enzymes or jaundice indicating liver stress.

Before starting Irbesartan, patients should consider the following precautions: - Blood pressure monitoring: regularly check to ensure therapeutic control. - Renal function assessment: evaluate serum creatinine and eGFR before and during therapy. - Serum potassium measurement: monitor for hyperkalemia, especially with concomitant potassium‑sparing agents. - Pregnancy: avoid use as safety in pregnancy is unknown; discuss alternatives with a healthcare professional. - Hepatic impairment: use with caution in patients with liver disease. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Irbesartan may interact with several medicines. Review the following groups: Major Interactions (Avoid): - Aliskiren (in diabetic patients): combined use can increase renal risk. - Dual ARB/ACE‑inhibitor therapy: may cause excessive potassium rise and kidney dysfunction. - Potassium‑sparing diuretics (e.g., spironolactone): heightens risk of hyperkalemia. Moderate Interactions (Monitor Closely): - NSAIDs (e.g., ibuprofen): can reduce antihypertensive effect and impair renal function. - Lithium: may increase lithium concentrations, requiring serum level checks.