Irbesartan/Hydrocholorthiazide Teva (Hydrochlorothiazide, Irbesartan)

Irbesartan, the active ingredient in Irbesartan/Hydrochlorothiazide Teva, is an angiotensin II receptor blocker presented as a combined tablet for oral use. It treats hypertension in adults, often together with hydrochlorothiazide.

GNH USA supplies Irbesartan/Hydrochlorothiazide Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Irbesartan/Hydrochlorothiazide is used in the management of cardiovascular conditions, primarily hypertension.

Hypertension: lowers systolic and diastolic blood pressure, helping to control essential high blood pressure.

Common Side Effects: - Dizziness or light‑headedness - Headache - Fatigue or weakness - Increased urination - Electrolyte disturbances (e.g., low potassium) - Mild gastrointestinal upset

Serious or Rare Side Effects: - Severe dehydration or electrolyte imbalance - Acute kidney injury or worsening renal function - Hyperkalemia or severe hyponatremia - Angioedema or severe allergic reaction - Significant hypotension - Pancreatitis (rare)

Before initiating therapy, consider the following precautions: - Blood pressure monitoring: ensure adequate control and avoid excessive lowering. - Renal function assessment: check serum creatinine and eGFR, especially in patients with pre‑existing kidney disease. - Electrolyte surveillance: monitor potassium and sodium levels regularly. - Diabetes mellitus: watch for changes in blood glucose as diuretics may affect glycemic control. - Pregnancy and lactation: use only if clearly needed after risk‑benefit evaluation. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Irbesartan/Hydrochlorothiazide may interact with several medicines.

Major Interactions (Avoid): - Potassium‑sparing diuretics or supplements: risk of hyperkalemia. - Lithium: increased lithium levels leading to toxicity. - ACE inhibitors or other ARBs: additive effect on blood pressure and renal function. - NSAIDs: may reduce antihypertensive efficacy and impair renal function.

Moderate Interactions (Monitor Closely): - Other antihypertensives: may cause excessive hypotension. - Antidiabetic agents: diuretic‑induced changes in glucose may require dose adjustment. - Corticosteroids: can increase sodium retention counteracting diuretic effect. - Antimicrobials such as trimethoprim‑sulfamethoxazole: may raise potassium levels.