Irbesartan/Hydrocholorthiazide Teva

Irbesartan/Hydrochlorothiazide, the active ingredient in Irbesartan/Hydrochlorothiazide Teva, is an angiotensin II receptor blocker / thiazide diuretic presented as an oral tablet for systemic use. It is prescribed to lower elevated blood pressure in adult patients with hypertension and to help reduce cardiovascular risk.

GNH USA supplies Irbesartan/Hydrochlorothiazide Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Irbesartan/Hydrochlorothiazide is used within the antihypertensive drug class to manage high blood pressure. - Primary hypertension: reduces systolic and diastolic pressure in patients with essential hypertension. - Secondary hypertension: assists in controlling blood pressure when hypertension is caused by another underlying condition. - Hypertensive urgency (as part of combination therapy): helps achieve target blood pressure when rapid reduction is needed under medical supervision.

Common Side Effects: - Dizziness or light‑headedness - Headache - Fatigue or weakness - Increased urinary frequency - Electrolyte disturbances (e.g., low potassium) - Mild gastrointestinal discomfort

Serious or Rare Side Effects: - Severe dehydration or electrolyte imbalance - Acute kidney injury or worsening renal function - Hyperkalemia or severe hypokalemia - Angioedema or severe allergic reaction - Significant hypotension leading to syncope - Hepatic dysfunction or jaundice

Before initiating therapy, clinicians should assess patient history and monitor relevant parameters. - Renal function: evaluate serum creatinine and eGFR prior to and during treatment. - Electrolytes: check potassium and sodium levels regularly. - Diabetes: monitor blood glucose as diuretics may affect glycemic control. - Hepatic impairment: use with caution in patients with severe liver disease. - Pregnancy and lactation: avoid unless clearly indicated by a physician. - Store at room temperature: keep in the original container, protect from moisture and light.

Irbesartan/Hydrochlorothiazide may interact with several medicines; careful review is essential. Major Interactions (Avoid): - Aliskiren in patients with diabetes or renal impairment - Potassium‑sparing diuretics or supplements (risk of hyperkalemia) - Lithium (increased lithium toxicity) - ACE inhibitors or other ARBs (excessive hypotension, renal dysfunction) - NSAIDs (reduced antihypertensive effect, renal risk)

Moderate Interactions (Monitor Closely): - Other antihypertensives (additive blood pressure lowering) - CYP2C9 inhibitors (e.g., fluconazole) may increase irbesartan levels - Loop diuretics (enhanced diuretic effect, electrolyte loss) - Antidiabetic agents (possible need for dose adjustment)