Irbesartan/Hydrocholorthiazide Teva

Irbesartan/Hydrochlorothiazide, the active ingredient in Irbesartan/Hydrochlorothiazide Teva, is an angiotensin II receptor blocker combined with a thiazide diuretic, presented as a tablet for oral use. It is prescribed to lower elevated blood pressure in adult patients, often when monotherapy does not provide adequate control.

GNH USA supplies Irbesartan/Hydrochlorothiazide Teva as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide with consistent quality and regulatory compliance and supporting local procurement processes through reliable logistics and documentation.

Irbesartan/Hydrochlorothiazide is used in the management of hypertension, a cardiovascular condition characterized by elevated arterial pressure.

- Essential hypertension: lowers systolic and diastolic blood pressure in patients with primary hypertension. - Hypertension associated with type 2 diabetes: helps achieve target blood pressure while offering renal protective effects. - Resistant hypertension: provides additive blood pressure reduction when single‑agent therapy is insufficient. - Hypertension in chronic kidney disease: contributes to blood pressure control and slows disease progression.

The combination may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Dizziness or light‑headedness - Headache - Increased urination - Electrolyte disturbances (e.g., low potassium)

Serious or Rare Side Effects: - Severe dehydration - Acute kidney injury - Allergic reactions such as rash or angioedema - Marked hypotension

Before initiating therapy, consider the following precautions to ensure safe use.

- Renal function: assess kidney function and adjust dose in impairment. - Electrolytes: monitor serum potassium and sodium levels regularly. - Diabetes: observe blood glucose as thiazides may affect glycemic control. - Concomitant antihypertensives: watch for additive blood pressure lowering. - Pregnancy and lactation: avoid use unless benefits outweigh risks. - Store at ambient temperature: keep tablets in original packaging, protect from moisture and light.

Irbesartan/Hydrochlorothiazide can interact with several medicines; awareness of the interaction level guides clinical decisions.

Major Interactions (Avoid): - Potassium‑sparing diuretics or supplements: risk of hyperkalemia. - Lithium: increased lithium levels leading to toxicity. - NSAIDs (e.g., ibuprofen, naproxen): may reduce antihypertensive effect and impair renal function.

Moderate Interactions (Monitor Closely): - ACE inhibitors or other ARBs: additive risk of renal dysfunction and hyperkalemia. - Antidiabetic agents: thiazide may raise blood glucose, requiring dose adjustment. - Antimicrobials such as trimethoprim‑sulfamethoxazole: can increase serum potassium.