Irbesartan Hydrochlorothiazide Dawa

Irbesartan/Hydrochlorothiazide, the active ingredients in Irbesartan Hydrochlorothiazide Dawa, are an angiotensin II receptor blocker and thiazide diuretic presented as an oral tablet for oral use. They treat hypertension in adult patients.

GNH USA supplies Irbesartan Hydrochlorothiazide Dawa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Irbesartan/HCTZ is indicated for conditions within the hypertension disease family, where it helps control elevated blood pressure.

- Hypertension: reduces systolic and diastolic blood pressure in adults. - Hypertension with diabetes: improves blood pressure control and may lessen renal risk. - Hypertension in chronic kidney disease: assists in achieving target blood pressure and slows disease progression.

The combination may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Dizziness or light‑headedness - Headache - Increased urination - Electrolyte disturbances (e.g., low potassium)

Serious or Rare Side Effects: - Severe dehydration - Acute kidney injury - Allergic reactions such as rash, angioedema, or anaphylaxis

Before prescribing Irbesartan/HCTZ, consider the following precautions.

- Renal function: assess kidney function and monitor serum creatinine. - Electrolytes: check potassium and sodium levels regularly. - Pregnancy: avoid use unless benefits outweigh risks; safety not established. - Concomitant drugs: use caution with other antihypertensives to prevent hypotension. - Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture.

Irbesartan/HCTZ can interact with several medicines; categorize interactions by clinical significance.

Major Interactions (Avoid): - Potassium‑sparing diuretics or supplements: risk of hyperkalaemia. - Lithium: increased lithium levels and toxicity. - ACE inhibitors or other ARBs: additive renal effects and hyperkalaemia.

Moderate Interactions (Monitor Closely): - NSAIDs: may reduce antihypertensive efficacy and affect renal function. - Antidiabetic agents: blood glucose may rise; monitor glycaemic control. - Cyclosporine or tacrolimus: possible increase in serum creatinine.