Irbesartan Comp Hexal

Irbesartan, the active ingredient in Irbesartan Comp Hexal, is an angiotensin II receptor blocker presented as an oral tablet for oral use. It is combined with hydrochlorothiazide to treat hypertension in adult patients. GNH USA supplies Irbesartan Comp Hexal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Irbesartan Comp Hexal is an antihypertensive combination that lowers elevated blood pressure by acting on the renin‑angiotensin system and promoting diuresis.

Hypertension: Reduces systolic and diastolic blood pressure, helping to prevent cardiovascular complications.

Irbesartan Comp Hexal may cause a range of adverse reactions. Patients should be aware of both common and serious possibilities.

Common Side Effects: - Dizziness or light‑headedness - Headache - Fatigue or weakness - Increased urination - Mild electrolyte disturbances (e.g., low potassium) - Gastrointestinal discomfort such as nausea

Serious or Rare Side Effects: - Severe hypotension - Acute kidney injury or worsening renal function - Hyperkalemia or severe electrolyte imbalance - Anaphylactic or severe allergic reactions - Pancreatitis - Blood dyscrasias such as agranulocytosis

Before initiating therapy, clinicians should evaluate patient‑specific factors and monitor relevant parameters. - Blood pressure monitoring: Check regularly to avoid excessive hypotension. - Renal function: Assess serum creatinine and eGFR before and during treatment. - Electrolytes: Monitor potassium and sodium levels, especially with concomitant diuretics. - Hepatic impairment: Use with caution in patients with liver disease. - Pregnancy: Avoid use during pregnancy due to potential fetal harm. - Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Irbesartan Comp Hexal can interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Aliskiren in diabetic patients: increased risk of renal impairment and hyperkalemia. - Potassium‑sparing diuretics or supplements: may cause dangerous hyperkalemia. - ACE inhibitors or other ARBs: additive effect on potassium and renal function. - High‑dose NSAIDs: can diminish antihypertensive effect and worsen kidney function.

Moderate Interactions (Monitor Closely): - Lithium: may increase lithium levels, risking toxicity. - Other antihypertensives: may enhance blood‑pressure lowering effect. - CYP3A4 inhibitors (e.g., ketoconazole): may raise irbesartan concentrations. - NSAIDs at usual doses: require periodic renal function checks.