GNH USA

Europe — EMA

Ipramol Steri-Neb

GNH USA supplies Ipramol Steri-Neb (Ipratropium bromide and salbutamol), a bronchodilator for COPD and asthma bronchospasm. Request a quote for supply.

Ipratropium Bromide, Salbutamol

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What is Ipratropium Bromide, Salbutamol?

Ipratropium bromide and salbutamol, the active ingredients in Ipramol Steri-Neb, are a combination bronchodilator presented as an inhalation solution for inhalation use. It treats bronchospasm associated with chronic obstructive pulmonary disease and asthma in adult patients.

GNH USA supplies Ipramol Steri-Neb as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ipratropium Bromide, Salbutamol used for?

Ipramol Steri-Neb, a combination bronchodilator, is used to manage airway obstruction in obstructive lung diseases.

- COPD: reduces bronchospasm and improves airflow during acute exacerbations. - Asthma: provides rapid relief of bronchoconstriction in acute asthma attacks. - Acute bronchospasm: offers prompt bronchodilation to alleviate sudden airway narrowing.

What are the side effects of Ipratropium Bromide, Salbutamol?

Adverse reactions to Ipramol Steri-Neb may vary in frequency and severity.

Common Side Effects: - Dry mouth: sensation of dryness in the oral cavity. - Cough: transient irritation leading to coughing. - Throat irritation: discomfort or soreness in the throat. - Tremor: mild shaking of hands or limbs. - Headache: mild to moderate head pain. - Palpitations: awareness of heart beating faster or irregularly.

Serious or Rare Side Effects: - Paradoxical bronchospasm: worsening of airway constriction after inhalation. - Tachyarrhythmia: rapid or irregular heart rhythm. - Angioedema: swelling of face, lips, or airway. - Severe hypersensitivity: rash, itching, or anaphylactic reaction. - Cardiac ischemia: chest pain due to reduced heart blood flow.

What precautions apply to Ipratropium Bromide, Salbutamol?

Before prescribing Ipramol Steri-Neb, clinicians should consider several safety precautions. - Cardiac assessment: evaluate for existing heart disease or arrhythmias. - Glaucoma caution: avoid in patients with narrow‑angle glaucoma. - Monitor paradoxical bronchospasm: watch for worsening breathing after first dose. - Hypersensitivity screening: ensure no known allergy to ipratropium or salbutamol. - Use with caution in severe COPD: adjust therapy based on response. - Store at ambient temperature: keep in original packaging, protect from moisture and light.

What does Ipratropium Bromide, Salbutamol interact with?

Ipramol Steri-Neb can interact with other medicines; some combinations require avoidance while others need monitoring.

Major Interactions (Avoid): - Non‑selective beta‑blockers: may diminish bronchodilator effect and provoke bronchospasm. - MAO inhibitors: increase risk of cardiovascular side effects when combined with salbutamol. - Anticholinergic overload: concurrent use of other anticholinergics can enhance dry‑mouth and urinary retention.

Moderate Interactions (Monitor Closely): - Diuretics: may exacerbate hypokalemia induced by salbutamol. - Theophylline: combined use can increase risk of tachycardia and tremor. - Tricyclic antidepressants: may potentiate cardiovascular effects. - Digoxin: salbutamol may raise serum digoxin levels, requiring monitoring.

Frequently asked questions

What is Ipramol Steri-Neb used for?+
Ipramol Steri-Neb is a prescription inhalation product that combines ipratropium bromide and salbutamol to relieve bronchospasm in patients with chronic obstructive pulmonary disease (COPD) and asthma. It provides rapid bronchodilation during acute episodes and can be used as a rescue medication to improve breathing.
How does ipratropium bromide work?+
Ipratropium bromide is an anticholinergic agent that blocks muscarinic (M3) receptors on airway smooth muscle. By preventing acetylcholine‑mediated contraction, it reduces bronchoconstriction and helps keep the airways open, especially in COPD where cholinergic tone is high.
How does salbutamol work?+
Salbutamol is a short‑acting β2‑adrenergic agonist. It binds to β2 receptors on bronchial smooth muscle, activating adenylate cyclase, increasing cyclic AMP, and causing muscle relaxation. This leads to quick bronchodilation, relieving acute asthma symptoms and exercise‑induced bronchospasm.
What is the usual dose of Ipramol Steri-Neb?+
The prescribed dose of Ipramol Steri-Neb is determined by the treating physician based on the patient’s condition, severity of symptoms, and response to therapy. Typical regimens involve one or two inhalations as needed for relief, but exact dosing must follow the clinician’s order.
Is Ipramol Steri-Neb safe in pregnancy or breastfeeding?+
Safety data for ipratropium bromide and salbutamol during pregnancy and lactation are limited, and the product is classified as “unknown” for pregnancy. Use only if the potential benefit justifies the potential risk to the fetus or infant, and discuss with a healthcare professional.
How do I order Ipramol Steri-Neb from GNH USA?+
To order Ipramol Steri-Neb, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Ipramol Steri-Neb compare with other bronchodilators?+
Ipramol Steri-Neb combines an anticholinergic (ipratropium) with a β2‑agonist (salbutamol), offering additive bronchodilation compared with single‑agent inhalers. This dual mechanism can provide faster and more sustained relief than either component alone, making it useful for patients who need both pathways targeted.
How should Ipramol Steri-Neb be stored and handled?+
Store Ipramol Steri-Neb at ambient temperature, preferably below 25 °C, in its original container. Protect the product from moisture, direct sunlight, and extreme temperatures. Keep the device clean according to the manufacturer’s instructions to maintain dose accuracy.
How is Ipramol Steri-Neb administered?+
The medication is delivered by inhalation using a metered‑dose inhaler or nebulizer, as directed by the prescriber. The patient inhales the dose deeply and holds the breath for a few seconds to allow optimal drug deposition in the lower airways.
What are the most serious risks to watch for when using Ipramol Steri-Neb?+
Serious risks include paradoxical bronchospasm, which can worsen breathing shortly after inhalation, and cardiovascular events such as tachyarrhythmia or angina, especially in patients with pre‑existing heart disease. Any signs of severe allergic reaction, swelling of the face or throat, or persistent chest pain require immediate medical attention.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ipratropium Bromide, Salbutamol
Route
Inhalation Use , Oral Use
Manufacturer
Teva Nederland B.V.
Origin
EU

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