Iprafeine

Ibuprofen and Caffeine, the active ingredient in Iprafeine, is a NSAID presented as an unspecified strength/tablet for oral use. It provides analgesic and anti‑inflammatory relief for common pain conditions in adults.

GNH USA supplies Iprafeine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Iprafeine, a combination of ibuprofen and caffeine, works within the prostaglandin pathway to relieve pain.

- Headache: reduces intensity and duration of tension‑type headaches. - Migraine: alleviates migraine attacks when taken early in the episode. - Dental pain: eases pain associated with dental procedures and postoperative discomfort. - Musculoskeletal pain: mitigates muscle, joint and back pain caused by strain or minor injury.

Common Side Effects: - Dyspepsia or stomach upset - Nausea or vomiting - Heartburn or acid reflux - Dizziness or light‑headedness - Insomnia or restlessness - Increased heart rate

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer perforation - Severe allergic reactions such as anaphylaxis - Elevated liver enzymes or hepatic injury - Acute renal impairment or failure - Severe skin reactions (e.g., Stevens‑Johnson syndrome) - Thrombotic events in high‑risk cardiovascular patients

Before using Iprafeine, consider the following precautions: - Assess gastrointestinal risk: avoid if you have a history of ulcers or bleeding. - Take with food or milk: reduces stomach irritation. - Avoid in known hypersensitivity to ibuprofen, other NSAIDs, or caffeine. - Use cautiously in cardiovascular disease: monitor blood pressure and heart rate. - Monitor renal function in patients with kidney disease or dehydration. - Store below 25°C: keep in the original pack, protect from moisture.

Iprafeine may interact with several medicines.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Corticosteroids: heightened ulcer risk. - Lithium: elevated lithium levels. - Methotrexate: reduced clearance, potential toxicity.

Moderate Interactions (Monitor Closely): - Antihypertensives (e.g., ACE inhibitors, diuretics): possible reduction in blood pressure control. - SSRIs or SNRIs: modest increase in bleeding tendency. - Oral contraceptives: may reduce contraceptive efficacy. - Caffeine‑containing products: risk of excess stimulation. - Diuretics: potential impact on renal function.