Iohexol Imax

Iohexol, the active ingredient in Iohexol Imax, is an iodinated contrast agent presented as a sterile solution for intra‑arterial, intrathecal, and intravenous administration. It enhances radiographic contrast by increasing X‑ray attenuation, facilitating detailed visualization during diagnostic imaging procedures such as computed tomography (CT), angiography, and urography in adult and pediatric patients.

GNH USA supplies Iohexol Imax as a licensed, GDP‑compliant product, providing reliable global distribution to hospitals, imaging centres, and clinics worldwide, with support for regulatory compliance, quality assurance, and timely delivery.

Iohexol is used as an iodinated radiographic contrast medium to improve X‑ray based imaging. - Computed Tomography (CT): Provides enhanced contrast for detailed cross‑sectional imaging. - Angiography: Improves vessel delineation for arterial and venous studies. - Urography: Highlights urinary tract structures for functional assessment. - Myelography (intrathecal): Supplies contrast for spinal canal visualization.

Adverse reactions may occur following administration of iodinated contrast agents.

Common Side Effects: - Warm sensation or flushing: Transient feeling of heat. - Nausea: Mild to moderate upset stomach. - Vomiting: Occasional emesis after injection. - Headache: Temporary mild headache. - Urticaria: Itchy skin rash. - Taste alteration: Metallic taste in mouth.

Serious or Rare Side Effects: - Anaphylactic reaction: Severe allergic response requiring emergency care. - Renal toxicity: Acute kidney injury, especially in patients with pre‑existing renal impairment. - Seizures: Neurological events in rare cases. - Hypotension: Significant drop in blood pressure. - Cardiac arrest: Life‑threatening cardiac event. - Pulmonary edema: Fluid accumulation in lungs.

Prior to use, clinicians should evaluate patient risk factors and follow appropriate monitoring. - Renal function assessment: Check serum creatinine and eGFR before administration. - Allergy screening: Verify history of iodine or contrast media reactions. - Thyroid status: Avoid in patients with uncontrolled hyperthyroidism. - Hydration: Ensure adequate fluid intake to reduce renal risk. - Dose minimization: Use the lowest effective volume for the imaging study. - Store at below 25°C: Keep in original packaging, protect from moisture and light.

Iohexol may interact with other medications, influencing safety or efficacy.

Major Interactions (Avoid): - Metformin: Risk of lactic acidosis; consider temporary discontinuation. - Thyroid hormone therapy: Excess iodine can alter hormone levels. - Nephrotoxic agents (e.g., aminoglycosides): Increased risk of renal injury.

Moderate Interactions (Monitor Closely): - NSAIDs: May compound renal stress. - Diuretics: Potential for volume depletion. - ACE inhibitors or ARBs: May affect renal perfusion. - Beta‑blockers: May mask tachycardia from contrast reaction. - Corticosteroids: May influence immune response.