Invicorp

Phentolamine Mesilate / Aviptadil, the active ingredient in Invicorp, is an alpha-adrenergic antagonist and vasoactive intestinal peptide analog presented as a formulation for intracavernous use. It is used to treat erectile dysfunction in adult males. GNH USA supplies Invicorp as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Invicorp acts on the penile vascular system to improve erectile function. - Erectile dysfunction (organic): enhances penile blood flow to achieve satisfactory erections. - Erectile dysfunction (post‑prostatectomy): facilitates recovery of erectile capacity after surgical nerve damage. - Erectile dysfunction (diabetes‑related): counteracts vascular insufficiency associated with diabetic neuropathy.

Common Side Effects: - Pain or discomfort at the injection site - Bruising or hematoma formation - Transient hypotension or dizziness - Headache or flushing - Mild nausea - Localized swelling

Serious or Rare Side Effects: - Priapism lasting longer than four hours - Severe hypotension leading to syncope - Allergic reactions such as rash, itching, or anaphylaxis - Cardiovascular events including myocardial ischemia - Infection at the injection site - Penile fibrosis or tissue damage

Precautions should be observed before and during use of Invicorp. - Cardiovascular assessment: evaluate heart disease risk before administration. - Nitrate therapy: avoid concurrent use due to risk of profound hypotension. - Blood pressure monitoring: check baseline and post‑injection values. - Medical supervision: only administer under qualified healthcare professional guidance. - Store at ambient temperature: keep in original packaging, protect from moisture and light.

Potential drug interactions must be considered. Major Interactions (Avoid): - Nitrates: may cause severe hypotension. - Alpha‑blockers: additive vasodilatory effect. - PDE5 inhibitors: increased risk of priapism. - Antihypertensives: excessive blood pressure drop. - Monoamine oxidase inhibitors: unpredictable vascular response.

Moderate Interactions (Monitor Closely): - Antihistamines: may blunt vasodilatory response. - Certain antidepressants: possible alteration of vascular tone. - Alcohol: can enhance hypotensive effects. - CYP450 modulators: may affect drug metabolism. - Other vasodilators: monitor for additive blood pressure changes.