GNH USA

Europe — EMA

Inuxair

GNH USA supplies Inuxair (Beclometasone/Formoterol), a corticosteroid/long‑acting β2‑agonist for asthma and COPD maintenance. Request a quote for supply.

Beclometasone Dipropionate, Formoterol Fumarate Dihydrate

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What is Beclometasone Dipropionate, Formoterol Fumarate Dihydrate?

Beclometasone dipropionate, the active ingredient in Inuxair, is a corticosteroid presented as an inhalation aerosol (pressurised metered‑dose inhaler) for inhalation use. It treats asthma and chronic obstructive pulmonary disease (COPD) as maintenance therapy in adults and adolescents. GNH USA supplies Inuxair as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Beclometasone Dipropionate, Formoterol Fumarate Dihydrate used for?

Inuxair combines a corticosteroid and a long‑acting β2‑agonist to provide maintenance therapy for obstructive airway diseases.

Asthma: reduces airway inflammation and improves symptom control. COPD: decreases exacerbations and enhances lung function. Exercise‑induced bronchoconstriction: offers prophylactic bronchodilation for activity‑related symptoms.

What are the side effects of Beclometasone Dipropionate, Formoterol Fumarate Dihydrate?

Common Side Effects: - Oral thrush or candidiasis - Hoarseness or voice change - Cough or throat irritation - Headache - Tremor - Dry mouth

Serious or Rare Side Effects: - Paradoxical bronchospasm - Severe allergic reaction (anaphylaxis) - Adrenal suppression with prolonged use - Pneumonia or respiratory infection - Cardiac arrhythmia or tachycardia - Significant hypokalemia

What precautions apply to Beclometasone Dipropionate, Formoterol Fumarate Dihydrate?

Before using Inuxair, consider the following precautions: - Assess inhaler technique: ensure correct use to achieve optimal dosing. - Monitor for oral candidiasis: rinse mouth after each inhalation. - Screen for cardiovascular disease: β2‑agonist may affect heart rate and rhythm. - Use the lowest effective dose: minimize systemic corticosteroid exposure. - Avoid use in patients with known hypersensitivity to any component. - Store at room temperature: keep inhaler in original pack, protect from moisture and heat.

What does Beclometasone Dipropionate, Formoterol Fumarate Dihydrate interact with?

Inuxair may interact with other medicines as follows:

Major Interactions (Avoid): - Beta‑blockers: can reduce bronchodilator effectiveness and precipitate bronchospasm. - MAO inhibitors or tricyclic antidepressants: may increase cardiovascular side effects. - Diuretics: can potentiate hypokalemia caused by the β2‑agonist.

Moderate Interactions (Monitor Closely): - Other inhaled corticosteroids: increase total systemic steroid load. - CYP3A4 inhibitors (e.g., ritonavir): may raise formoterol plasma concentrations. - Theophylline: additive bronchodilator effect may increase risk of side effects.

Frequently asked questions

What is Inuxair used for?+
Inuxair is a fixed‑dose combination inhaler containing beclometasone dipropionate and formoterol fumarate dihydrate. It is indicated for maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD) in adults and adolescents, helping to control symptoms, reduce exacerbations and improve lung function when used regularly as prescribed.
How does beclometasone dipropionate work?+
Beclometasone dipropionate is a synthetic glucocorticoid that binds to intracellular glucocorticoid receptors in airway cells. This interaction modulates gene transcription, suppressing the production of inflammatory cytokines, chemokines and adhesion molecules, thereby reducing airway inflammation and hyper‑responsiveness.
How does formoterol fumarate dihydrate work?+
Formoterol is a selective long‑acting β2‑adrenergic receptor agonist. Activation of β2 receptors on bronchial smooth muscle increases intracellular cyclic AMP, leading to relaxation of the airway smooth muscle and bronchodilation that lasts for up to 12 hours, providing symptom relief.
What is the usual dose of Inuxair?+
The prescribed dose of Inuxair is individualized by the treating physician based on disease severity, patient age, and response to therapy. The prescriber determines the number of inhalations per day and may adjust the regimen during follow‑up visits; patients should follow the specific instructions on the prescription label.
How do I order Inuxair from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Inuxair compare with other asthma inhalers?+
Inuxair combines an inhaled corticosteroid with a long‑acting β2‑agonist in a single device, offering both anti‑inflammatory and bronchodilator effects. Compared with single‑component inhalers, it reduces the need for multiple devices and can improve adherence, while providing comparable efficacy to other combination products such as budesonide/formoterol or fluticasone/salmeterol.
How should Inuxair be stored?+
Inuxair should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and heat. Do not expose the inhaler to extreme temperatures or direct sunlight, and keep the mouthpiece clean to maintain proper dosing performance.
How is Inuxair administered?+
Inuxair is delivered via a pressurised metered‑dose inhaler. The patient should shake the inhaler, exhale fully, place the mouthpiece between the lips, and press the canister while inhaling slowly and deeply. After each dose, hold the breath for about 10 seconds, then exhale gently. Rinsing the mouth after use helps reduce oral side effects.
What are the most serious risks associated with Inuxair?+
Serious adverse events, although rare, can include paradoxical bronchospasm, severe allergic reactions such as anaphylaxis, adrenal suppression from prolonged corticosteroid exposure, and cardiovascular effects like tachycardia or arrhythmias due to the β2‑agonist component. Patients should seek immediate medical attention if they experience sudden worsening of breathing, swelling, or chest pain.
Who should not use Inuxair?+
Inuxair is contraindicated in individuals with known hypersensitivity to beclometasone dipropionate, formoterol fumarate, or any excipients in the inhaler. It should also be avoided in patients who have experienced severe asthma attacks requiring oral corticosteroids, or in those with certain cardiac conditions where β2‑agonists may be unsafe, unless a physician determines that benefits outweigh risks.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Beclometasone Dipropionate, Formoterol Fumarate Dihydrate
Route
Inhalation Use
Manufacturer
Chiesi Farmaceutici S.P.A.
Origin
EU

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