GNH USA

Europe — EMA

Inuver

GNH USA supplies Inuver (Beclometasone/Formoterol), a inhaled corticosteroid/long‑acting β2‑agonist for asthma and COPD. Request a quote for global supply.

Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous

Request sourcing

1
Pack/s

What is Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous?

Beclometasone dipropionate / Formoterol fumarate, the active ingredient in Inuver, is an inhaled corticosteroid/long‑acting β2‑agonist combination presented as an inhalation product for inhalation use. It treats asthma and chronic obstructive pulmonary disease (COPD) in adult patients by reducing airway inflammation and providing sustained bronchodilation. The formulation is designed for delivery via a metered‑dose inhaler, ensuring rapid deposition in the lower respiratory tract.

GNH USA supplies Inuver as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality and regulatory compliance.

What is Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous used for?

Inuver combines an inhaled corticosteroid with a long‑acting β2‑agonist to manage chronic airway diseases.

Asthma: improves symptom control and reduces the frequency of exacerbations COPD: enhances lung function and decreases breathlessness during daily activities Bronchial hyperresponsiveness: provides maintenance bronchodilation and anti‑inflammatory effect

What are the side effects of Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous?

Inhalation of Inuver may be associated with a range of adverse reactions, which are categorized by frequency.

Common Side Effects: - Throat irritation or soreness - Oral candidiasis (thrush) - Headache

Serious or Rare Side Effects: - Paradoxical bronchospasm - Severe allergic reaction (anaphylaxis) - Adrenal suppression with prolonged high‑dose use

What precautions apply to Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous?

Before using Inuver, patients and clinicians should consider several safety measures.

Assess asthma or COPD control before initiating therapy: ensure patient is stable Monitor for oral thrush: advise rinsing mouth after each inhalation Use the lowest effective dose to maintain symptom control Avoid abrupt discontinuation: taper under medical supervision Caution in patients with cardiovascular disease: monitor heart rate and blood pressure Store at ambient temperature: keep in original container, protect from moisture and heat

What does Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous interact with?

Inuver may interact with other medicines; awareness of these interactions helps maintain safety.

Major Interactions (Avoid): - Non‑selective beta‑blockers: may diminish bronchodilator effect and precipitate bronchospasm - Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): increase systemic exposure to both components - Diuretics (e.g., furosemide): may potentiate hypokalemia when combined with formoterol

Moderate Interactions (Monitor Closely): - Diabetes medications: β2‑agonist may raise blood glucose levels - Theophylline: additive stimulant effect on the cardiovascular system - Vaccines (live attenuated): inhaled steroids may reduce immune response

Frequently asked questions

What is Inuver used for?+
Inuver is a prescription inhalation medication that combines beclometasone dipropionate, an inhaled corticosteroid, with formoterol fumarate, a long‑acting β2‑agonist. It is indicated for the maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD) in adults, helping to control symptoms, reduce inflammation, and improve lung function.
How does beclometasone dipropionate work?+
Beclometasone dipropionate binds to glucocorticoid receptors in airway epithelial and inflammatory cells. This interaction modulates gene expression, suppressing the production of cytokines, chemokines, and other mediators that drive airway inflammation, thereby decreasing swelling, mucus production and hyper‑responsiveness.
How does formoterol fumarate work?+
Formoterol fumarate is a selective long‑acting β2‑adrenergic agonist. It activates β2 receptors on bronchial smooth muscle, stimulating adenylate cyclase and raising intracellular cyclic AMP levels. The rise in cAMP leads to relaxation of smooth muscle and inhibition of mast cell mediator release, providing sustained bronchodilation for up to 12 hours.
What is the usual dose of Inuver?+
The prescribed dose of Inuver is determined individually by a qualified healthcare professional based on the severity of the patient’s asthma or COPD, age, and response to therapy. The prescriber selects the appropriate number of inhalations per day and may adjust the regimen during follow‑up visits. No generic dosing information is provided here.
Is Inuver safe during pregnancy or breastfeeding?+
Safety data for beclometasone dipropionate and formoterol fumarate in pregnancy or lactation are limited. The medication should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers should discuss risks and consider alternative treatments when appropriate.
How do I order Inuver from GNH USA?+
To place an order, submit an enquiry on the Inuver product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. The sales team then provides pricing, availability, shipping details (including any cold‑chain requirements) and assists with import documentation.
How does Inuver compare with other inhaled therapies?+
Compared with single‑component inhalers, the fixed‑dose combination of beclometasone and formoterol offers both anti‑inflammatory and bronchodilator actions in one device, which can improve adherence and simplify regimens. Alternatives such as separate inhaled corticosteroid and short‑acting β2‑agonist inhalers require multiple steps, while other LABA/ICS combos may differ in potency, dosing frequency or device type.
How should Inuver be stored and handled?+
Inuver inhalers should be stored at ambient temperature, preferably below 25 °C, in the original packaging to protect the device from moisture and direct sunlight. Keep the inhaler out of reach of children and avoid exposing it to extreme heat or freezing conditions, which could affect the dose‑metering mechanism.
How is Inuver administered?+
Inuver is delivered via a metered‑dose inhaler. The patient should exhale fully, place the mouthpiece in the mouth, seal lips around it, and press the canister to release a puff while inhaling slowly and deeply. After inhalation, hold the breath for a few seconds, then exhale. The device should be primed according to the manufacturer’s instructions before first use and periodically as recommended.
Who should not use Inuver?+
Inuver is contraindicated in patients with a known hypersensitivity to beclometasone, formoterol, or any excipients in the inhaler. It should also be avoided in individuals who have experienced a severe paradoxical bronchospasm with β2‑agonists. Caution is advised for patients with uncontrolled cardiovascular disorders, such as arrhythmias or hypertension, and for those receiving non‑selective beta‑blockers.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous
Route
Inhalation Use
Manufacturer
Chiesi Farmaceutici S.P.A.
Origin
EU

Related products