GNH USA

USA — NDC

Intuniv XR 2 mg

GNH USA supplies Intuniv XR 2 mg (Guanfacine), an alpha-2A adrenergic agonist for ADHD. Request a quote for global supply.

Guanfacine (Guanfacine Hydrochloride)
INTUNIV XR
TABLET (EXTENDED-RELEASE)
2 MG

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1
Pack/s

What is Guanfacine (Guanfacine Hydrochloride)?

Guanfacine, the active ingredient in Intuniv XR 2 mg, is an alpha-2A adrenergic agonist presented as a 2 mg extended-release tablet for oral use. It is used to treat attention deficit hyperactivity disorder (ADHD) in children and adolescents and is also used off-label for hypertension. GNH USA supplies Intuniv XR 2 mg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Intuniv XR 2 mg is a non-stimulant medication that helps manage symptoms of ADHD, such as inattention, hyperactivity, and impulsivity. It works by affecting certain receptors in the brain to improve attention and impulse control. This extended-release formulation ensures a steady release of the medication over time, providing consistent therapeutic effects.

What is Guanfacine (Guanfacine Hydrochloride) used for?

Intuniv XR 2 mg is primarily used to manage symptoms of attention deficit hyperactivity disorder (ADHD) in children and adolescents. It is also used off-label for the treatment of hypertension.

- ADHD: Helps improve attention, reduce hyperactivity, and control impulsivity in children and adolescents with ADHD. - Hypertension: May be used to lower blood pressure, though this is an off-label use. - As adjunctive therapy: Can be used alongside psychostimulants for ADHD treatment in patients who do not respond adequately to other non-stimulant alternatives. - Monotherapy: May be used as a single therapy for patients who cannot tolerate psychostimulants or have had an inadequate response to other non-stimulant treatments.

What are the side effects of Guanfacine (Guanfacine Hydrochloride)?

Intuniv XR 2 mg may cause various side effects, ranging from common to serious. It is important to be aware of these potential effects and consult a healthcare provider if they occur.

Common Side Effects: - Drowsiness: May cause drowsiness, especially when starting the medication or increasing the dose. - Dizziness: Some patients may experience dizziness or lightheadedness. - Dry mouth: A common side effect that can be managed with good oral hygiene. - Fatigue: May cause a feeling of tiredness or lack of energy. - Headache: Some patients may experience mild to moderate headaches. - Constipation: May occur due to the medication's effects on the gastrointestinal system.

Serious or Rare Side Effects: - Low blood pressure: May cause a significant drop in blood pressure, leading to fainting or dizziness. - Slow heart rate: Can result in bradycardia, which may require medical attention. - Allergic reactions: Rare but possible, with symptoms such as rash, itching, or swelling. - Mood changes: May include depression, irritability, or changes in mood. - Vision changes: Blurred vision or other visual disturbances may occur.

What precautions apply to Guanfacine (Guanfacine Hydrochloride)?

Intuniv XR 2 mg should be used with caution and under the supervision of a healthcare provider. Certain precautions and warnings should be considered to ensure safe and effective use.

- Avoid alcohol: Consuming alcohol while taking guanfacine may increase the risk of side effects such as drowsiness and dizziness. - Avoid high-fat meals: Taking guanfacine with a high-fat meal may increase the absorption of the medication, leading to increased side effects. - Gradual dose increases: The dose should be increased gradually to minimize the risk of side effects. - Monitor blood pressure: Regular monitoring of blood pressure is important, especially in patients with hypertension. - Swallow whole: The extended-release tablets should be swallowed whole and not crushed, chewed, or split. - Store below 25°C: Keep in the original pack, protect from moisture.

What does Guanfacine (Guanfacine Hydrochloride) interact with?

Intuniv XR 2 mg may interact with other medications, potentially altering its effectiveness or increasing the risk of side effects. It is important to inform your healthcare provider about all medications you are taking.

Major Interactions (Avoid): - CNS depressants: Avoid taking guanfacine with other central nervous system (CNS) depressants, as this may increase the risk of excessive sedation. - Other antihypertensives: Avoid combining guanfacine with other antihypertensive medications without medical supervision to prevent excessive blood pressure lowering. - Alcohol: Avoid consuming alcohol while taking guanfacine, as it may increase the risk of drowsiness and dizziness.

Moderate Interactions (Monitor Closely): - Beta-blockers: Monitor closely when combining guanfacine with beta-blockers, as this may enhance the blood pressure-lowering effects. - Antidepressants: Monitor for increased side effects such as drowsiness or dizziness when taking guanfacine with antidepressants. - Antipsychotics: Monitor for increased side effects such as drowsiness or dizziness when taking guanfacine with antipsychotics.

Frequently asked questions

What is Intuniv XR 2 mg used for?+
Intuniv XR 2 mg is primarily used to treat attention deficit hyperactivity disorder (ADHD) in children and adolescents. It helps improve attention, reduce hyperactivity, and control impulsivity. It is also used off-label for the treatment of hypertension, though this is not its primary indication.
How does Guanfacine work?+
Guanfacine works by selectively activating post-synaptic alpha-2A adrenergic receptors in the prefrontal cortex. This action decreases sympathetic outflow and enhances attention and impulse control. By modulating these receptors, guanfacine helps to strengthen working memory, reduce distraction, and improve overall focus and behavior in individuals with ADHD.
What is the usual dose of Intuniv XR 2 mg?+
The usual dose of Intuniv XR 2 mg is determined by a healthcare provider based on the individual's needs and response to the medication. It is important to follow the prescribed dosage and not to adjust it without medical supervision.
Is Intuniv XR 2 mg safe during pregnancy or breastfeeding?+
The safety of Intuniv XR 2 mg during pregnancy or breastfeeding has not been established. It is important to consult a healthcare provider before taking this medication if you are pregnant, planning to become pregnant, or breastfeeding.
How do I order Intuniv XR 2 mg from GNH USA?+
To order Intuniv XR 2 mg from GNH USA, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will reply with pricing, availability, shipping, and the import paperwork.
How does Intuniv XR 2 mg compare to other ADHD medications?+
Intuniv XR 2 mg is a non-stimulant medication, unlike many other ADHD medications that are stimulants. It is often used as an alternative for patients who cannot tolerate stimulants or have had an inadequate response to other treatments. It works by affecting certain receptors in the brain to improve attention and impulse control.
How should Intuniv XR 2 mg be stored and handled?+
Intuniv XR 2 mg should be stored below 25°C, kept in the original pack, and protected from moisture. The extended-release tablets should be swallowed whole and not crushed, chewed, or split. It is important to follow the storage instructions to maintain the medication's effectiveness.
How is Intuniv XR 2 mg administered?+
Intuniv XR 2 mg is taken orally, usually once daily in the morning or evening. It should be taken as directed by a healthcare provider, and the tablets should be swallowed whole with a small amount of water or another liquid. It is important not to take this medication with a high-fat meal, as this may increase the absorption of the drug and lead to increased side effects.
What are the most serious risks to watch for with Intuniv XR 2 mg?+
The most serious risks to watch for with Intuniv XR 2 mg include low blood pressure, slow heart rate, allergic reactions, and mood changes. It is important to monitor for these side effects and consult a healthcare provider if they occur. Regular monitoring of blood pressure is also important, especially in patients with hypertension.
Who should not use Intuniv XR 2 mg?+
Intuniv XR 2 mg should not be used by individuals who are allergic to guanfacine or any of its ingredients. It should also be used with caution in patients with certain medical conditions, such as heart problems or low blood pressure. It is important to consult a healthcare provider before starting this medication to ensure it is safe and appropriate for you.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Guanfacine (Guanfacine Hydrochloride)
Brand
INTUNIV XR
Strength
2 MG
Form
TABLET (EXTENDED-RELEASE)
Route
ORAL
Manufacturer
TAKEDA CANADA INC
Origin
CANADA

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