Europe — EMA
Intizol Vaginal
GNH USA supplies Intizol Vaginal (Metronidazole), a Nitroimidazole antibiotic for bacterial vaginosis, trichomoniasis and other vaginal infections.
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What is Metronidazole?
Metronidazole, the active ingredient in Intizol Vaginal, is a Nitroimidazole presented as a vaginal formulation for local use. It treats anaerobic bacterial and protozoal infections of the vagina in adult women. GNH USA supplies Intizol Vaginal as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Metronidazole used for?
Intizol Vaginal contains metronidazole, an antibiotic that targets anaerobic microorganisms responsible for common vaginal infections. - Bacterial vaginosis: reduces overgrowth of anaerobic bacteria and helps restore normal vaginal flora. - Trichomoniasis: eliminates the protozoan Trichomonas vaginalis, relieving symptoms and preventing recurrence. - Other vaginal infections: provides antimicrobial activity against susceptible anaerobic pathogens causing vaginitis.
What are the side effects of Metronidazole?
Intizol Vaginal may cause adverse reactions, most of which are mild and reversible.
Common Side Effects: - Vaginal irritation or burning: mild discomfort at the site of application. - Abnormal discharge: temporary changes in vaginal secretions. - Headache: occasional mild headache. - Nausea: transient feeling of nausea. - Metallic taste: occasional taste disturbance. - Itching: mild pruritus of the vulvar area.
Serious or Rare Side Effects: - Allergic reaction: rash, swelling, or difficulty breathing. - Stevens‑Johnson syndrome: severe skin blistering and mucosal involvement. - Seizures: rare neurologic events. - Liver toxicity: elevated liver enzymes or hepatitis. - Severe nausea/vomiting: persistent gastrointestinal upset. - Hematologic changes: unexplained bruising or bleeding.
What precautions apply to Metronidazole?
Intizol Vaginal should be used with caution and according to medical guidance. - Pregnancy: Category B, generally considered safe but use only if clearly needed. - Breastfeeding: Small amounts may be excreted in milk; consult a healthcare professional. - Alcohol: Avoid alcohol to prevent a disulfiram‑like reaction. - Duration: Do not exceed prescribed treatment length to reduce resistance risk. - Hypersensitivity: Discontinue if signs of allergic reaction appear. - Store at room temperature: keep in original packaging, protect from moisture and direct sunlight.
What does Metronidazole interact with?
Metronidazole can interact with several medicines, requiring attention to avoid adverse outcomes.
Major Interactions (Avoid): - Alcohol: may cause severe flushing, nausea, and tachycardia. - Warfarin: increased anticoagulant effect, raising bleeding risk. - Lithium: heightened lithium toxicity.
Moderate Interactions (Monitor Closely): - Carbamazepine: may reduce metronidazole plasma levels. - Cimetidine: can increase metronidazole concentrations. - Rifampin: may decrease metronidazole effectiveness.
Frequently asked questions
What is Intizol Vaginal used for?+
How does metronidazole work?+
What is the usual dose of Intizol Vaginal?+
Is Intizol Vaginal safe during pregnancy or breastfeeding?+
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Product details
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