Intertos

Dextromethorphan, the active ingredient in Intertos, is a cough suppressant presented as an oral formulation for oral use. It is used to relieve non‑productive cough in adults and children when a dry cough interferes with daily activities or sleep. It works by modulating the cough reflex in the brain and is available without a prescription in the European market.

GNH USA supplies Intertos as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance.

Dextromethorphan is an antitussive that acts on the central cough reflex.

- Non‑productive cough: reduces cough frequency and severity in dry cough conditions. - Upper respiratory tract infection cough: provides symptomatic relief of irritation‑induced cough. - Acute bronchitis cough: helps suppress a dry cough associated with bronchial inflammation.

Dextromethorphan may cause a range of adverse reactions.

Common Side Effects: - Drowsiness: mild sedation or feeling of sleepiness. - Dizziness: sensation of light‑headedness or unsteadiness. - Nausea: upset stomach or urge to vomit. - Vomiting: expulsion of stomach contents. - Constipation: reduced bowel movements. - Dry mouth: decreased salivation.

Serious or Rare Side Effects: - Allergic reactions: rash, itching, swelling, or hives. - Hallucinations or psychotic symptoms: visual or auditory disturbances. - Respiratory depression: slowed breathing at high doses. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Seizures: rare occurrence of convulsive episodes.

When using Intertos, consider the following precautions.

- Pregnancy: Category B1; use only if clearly needed after risk assessment. - Asthma or COPD: Caution in patients with underlying respiratory disorders. - Alcohol consumption: Avoid or limit alcohol as it may increase sedation. - Driving and machinery: Do not operate vehicles or heavy equipment if drowsy. - Children under 12 years: Use only under medical supervision. - Store at ambient temperature: keep in the original pack, protect from moisture and light.

Dextromethorphan can interact with several medicines.

Major Interactions (Avoid): - MAO inhibitors: risk of severe hypertension. - CNS depressants (e.g., opioids, benzodiazepines): additive sedation and respiratory depression. - SSRIs or SNRIs: potential for serotonin syndrome.

Moderate Interactions (Monitor Closely): - Antihistamines: may increase drowsiness. - Alcohol: enhances central nervous system depression. - Ritonavir: may raise dextromethorphan plasma concentrations.