GNH USA

Europe — EMA

Instillagel - Einmalspritze

GNH USA supplies Instillagel - Einmalspritze (chlorhexidine gluconate, lidocaine hydrochloride), a urinary antiseptic and local anaesthetic

Chlorhexidine Gluconate, Lidocaine Hydrochloride

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What is Chlorhexidine Gluconate, Lidocaine Hydrochloride?

Chlorhexidine gluconate, the active ingredient in Instillagel - Einmalspritze, is an antiseptic; lidocaine hydrochloride is a local anesthetic presented as a gel in a single‑use syringe for urethral use. It provides antiseptic protection and local anaesthesia during catheterisation and other urethral procedures.

GNH USA supplies Instillagel - Einmalspritze as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

What is Chlorhexidine Gluconate, Lidocaine Hydrochloride used for?

Instillagel - Einmalspritze combines an antiseptic and a local anaesthetic for use in the urinary tract.

- Prophylaxis of urinary tract infections during catheterisation: reduces bacterial colonisation of the urethra. - Local anaesthesia for urethral procedures: provides reversible loss of sensation to facilitate instrumentation. - Disinfection of the urethra prior to instrumentation: prepares the urethral mucosa for safe catheter or endoscopic entry.

What are the side effects of Chlorhexidine Gluconate, Lidocaine Hydrochloride?

Instillagel - Einmalspritze may cause local or systemic reactions, although most patients tolerate it well.

Common Side Effects: - Burning sensation: mild transient discomfort at the application site. - Stinging or itching: brief irritation of urethral mucosa. - Redness or mild inflammation: localized erythema that resolves spontaneously.

Serious or Rare Side Effects: - Allergic reaction: urticaria, angioedema, or anaphylaxis requiring immediate medical attention. - Severe urethral irritation: persistent pain, ulceration, or bleeding. - Systemic toxicity: signs of lidocaine overdose such as dizziness, tinnitus, or cardiac arrhythmia (rare).

What precautions apply to Chlorhexidine Gluconate, Lidocaine Hydrochloride?

When using Instillagel - Einmalspritze, observe the following precautions to ensure safety and effectiveness.

- Patient assessment: verify no known hypersensitivity to chlorhexidine, lidocaine, or related compounds. - Contraindications: avoid in patients with a history of severe allergic reactions to the ingredients. - Use in pregnancy: limit use to situations where benefit outweighs potential risk; consult obstetric guidance. - Use in breastfeeding: consider potential exposure to infant; discuss with healthcare provider. - Interaction with other urethral agents: do not combine with other antiseptics or anesthetics without professional advice. - Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

What does Chlorhexidine Gluconate, Lidocaine Hydrochloride interact with?

Instillagel - Einmalspritze can interact with certain medications or substances; awareness of these interactions helps prevent adverse outcomes.

Major Interactions (Avoid): - Other local anesthetics: concurrent use may increase risk of systemic lidocaine toxicity. - Systemic chlorhexidine exposure: combined use may enhance irritation or allergic response.

Moderate Interactions (Monitor Closely): - Anticoagulants: urethral irritation may increase bleeding risk; monitor for hematuria. - Beta‑blockers: may potentiate lidocaine’s cardiac effects; observe heart rate and rhythm. - Certain antibiotics (e.g., aminoglycosides): potential additive nephrotoxicity in patients with compromised renal function.

Frequently asked questions

What is Instillagel - Einmalspritze used for?+
Instillagel - Einmalspritze is used to provide antiseptic protection and local anaesthesia of the urethra during catheterisation, urethral instrumentation, and other related procedures. It helps prevent urinary tract infections and reduces discomfort by disinfecting the mucosa and numbing the area.
How does chlorhexidine gluconate work?+
Chlorhexidine gluconate acts by binding to bacterial cell membranes, disrupting their integrity and causing leakage of intracellular contents, which leads to cell death. This broad‑spectrum antimicrobial activity makes it effective for reducing bacterial colonisation on the urethral surface.
What is the usual dose of Instillagel - Einmalspritze?+
The dose of Instillagel - Einmalspritze is determined by the prescribing clinician based on the specific procedure and patient needs. The product is supplied in a single‑use syringe that delivers the appropriate volume for urethral application.
Is Instillagel - Einmalspritze safe in pregnancy or breastfeeding?+
Safety data are limited; therefore, use during pregnancy or breastfeeding should only be considered when the expected benefit justifies any potential risk. Clinicians should evaluate each case individually and discuss possible effects with the patient.
How do I order Instillagel - Einmalspritze from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and import documentation.
How does Instillagel compare with the main alternative drug or class?+
The most common alternative is povidone‑iodine solution combined with a separate local anaesthetic. Instillagel offers a single‑dose, ready‑to‑use gel that combines both antiseptic and anaesthetic functions, reducing preparation steps and potential incompatibility issues while delivering comparable antimicrobial efficacy.
What are the storage and handling requirements for Instillagel - Einmalspritze?+
Store the product at ambient temperature, preferably below 25 °C, in its original sealed packaging. Protect it from moisture, direct sunlight and extreme temperatures. Do not freeze or expose the syringe to mechanical shock before use.
How is Instillagel - Einmalspritze administered?+
The gel is supplied in a sterile, single‑use syringe. After proper aseptic preparation, the clinician instills the gel directly into the urethra using the syringe tip, allowing the solution to coat the mucosa before catheter insertion or other instrumentation.
What are the most serious risks to watch for when using Instillagel - Einmalspritze?+
Serious risks include allergic reactions such as urticaria, angioedema or anaphylaxis, severe urethral irritation leading to ulceration or bleeding, and rare systemic lidocaine toxicity presenting as dizziness, tinnitus, or cardiac arrhythmias. Immediate medical attention is required if any of these occur.
Who should not use Instillagel - Einmalspritze?+
Patients with a known hypersensitivity to chlorhexidine, lidocaine, or any component of the formulation should avoid using the product. It is also contraindicated in individuals who have experienced severe allergic reactions to similar antiseptics or local anaesthetics.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Chlorhexidine Gluconate, Lidocaine Hydrochloride
Route
Urethral Use
Manufacturer
Farco-Pharma Gmbh
Origin
EU

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