Europe — EMA
Instillagel - Einmalspritze
GNH USA supplies Instillagel - Einmalspritze (chlorhexidine gluconate, lidocaine hydrochloride), a urinary antiseptic and local anaesthetic
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What is Chlorhexidine Gluconate, Lidocaine Hydrochloride?
Chlorhexidine gluconate, the active ingredient in Instillagel - Einmalspritze, is an antiseptic; lidocaine hydrochloride is a local anesthetic presented as a gel in a single‑use syringe for urethral use. It provides antiseptic protection and local anaesthesia during catheterisation and other urethral procedures.
GNH USA supplies Instillagel - Einmalspritze as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and clinics worldwide.
What is Chlorhexidine Gluconate, Lidocaine Hydrochloride used for?
Instillagel - Einmalspritze combines an antiseptic and a local anaesthetic for use in the urinary tract.
- Prophylaxis of urinary tract infections during catheterisation: reduces bacterial colonisation of the urethra. - Local anaesthesia for urethral procedures: provides reversible loss of sensation to facilitate instrumentation. - Disinfection of the urethra prior to instrumentation: prepares the urethral mucosa for safe catheter or endoscopic entry.
What are the side effects of Chlorhexidine Gluconate, Lidocaine Hydrochloride?
Instillagel - Einmalspritze may cause local or systemic reactions, although most patients tolerate it well.
Common Side Effects: - Burning sensation: mild transient discomfort at the application site. - Stinging or itching: brief irritation of urethral mucosa. - Redness or mild inflammation: localized erythema that resolves spontaneously.
Serious or Rare Side Effects: - Allergic reaction: urticaria, angioedema, or anaphylaxis requiring immediate medical attention. - Severe urethral irritation: persistent pain, ulceration, or bleeding. - Systemic toxicity: signs of lidocaine overdose such as dizziness, tinnitus, or cardiac arrhythmia (rare).
What precautions apply to Chlorhexidine Gluconate, Lidocaine Hydrochloride?
When using Instillagel - Einmalspritze, observe the following precautions to ensure safety and effectiveness.
- Patient assessment: verify no known hypersensitivity to chlorhexidine, lidocaine, or related compounds. - Contraindications: avoid in patients with a history of severe allergic reactions to the ingredients. - Use in pregnancy: limit use to situations where benefit outweighs potential risk; consult obstetric guidance. - Use in breastfeeding: consider potential exposure to infant; discuss with healthcare provider. - Interaction with other urethral agents: do not combine with other antiseptics or anesthetics without professional advice. - Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.
What does Chlorhexidine Gluconate, Lidocaine Hydrochloride interact with?
Instillagel - Einmalspritze can interact with certain medications or substances; awareness of these interactions helps prevent adverse outcomes.
Major Interactions (Avoid): - Other local anesthetics: concurrent use may increase risk of systemic lidocaine toxicity. - Systemic chlorhexidine exposure: combined use may enhance irritation or allergic response.
Moderate Interactions (Monitor Closely): - Anticoagulants: urethral irritation may increase bleeding risk; monitor for hematuria. - Beta‑blockers: may potentiate lidocaine’s cardiac effects; observe heart rate and rhythm. - Certain antibiotics (e.g., aminoglycosides): potential additive nephrotoxicity in patients with compromised renal function.
Frequently asked questions
What is Instillagel - Einmalspritze used for?+
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Product details
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