GNH USA

Europe — EMA

Instillagel

GNH USA supplies Instillagel (Chlorhexidine Gluconate, Lidocaine Hydrochloride), a urogenital antiseptic and analgesic for catheter‑related infection

Chlorhexidine Gluconate, Lidocaine Hydrochloride

Request sourcing

1
Pack/s

What is Chlorhexidine Gluconate, Lidocaine Hydrochloride?

Chlorhexidine Gluconate and Lidocaine Hydrochloride, the active ingredients in Instillagel, are an antiseptic and a local anesthetic presented as a gel for urethral use. They help prevent infection and relieve discomfort during catheterisation procedures. GNH USA supplies Instillagel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Chlorhexidine Gluconate, Lidocaine Hydrochloride used for?

Instillagel, a combination antiseptic and local anesthetic gel, is used in the urogenital tract to prevent infection and reduce discomfort during catheterisation. - Catheter‑associated urinary tract infection prevention: reduces bacterial colonisation during catheter insertion. - Urethral pain relief: provides local anaesthesia to alleviate discomfort associated with catheterisation. - Pre‑procedural urethral preparation: cleanses the urethra before diagnostic or therapeutic procedures.

What are the side effects of Chlorhexidine Gluconate, Lidocaine Hydrochloride?

Instillagel may cause local reactions after urethral application.

Common Side Effects: - Burning or stinging sensation at the application site. - Mild urethral irritation or redness. - Transient urinary urgency or frequency. - Mild allergic skin reaction such as rash.

Serious or Rare Side Effects: - Anaphylaxis or severe hypersensitivity reaction. - Severe urethral inflammation or chemical cystitis. - Tissue necrosis or ulceration at the site of application.

What precautions apply to Chlorhexidine Gluconate, Lidocaine Hydrochloride?

Before using Instillagel, consider the following precautions. - Allergy assessment: verify no known hypersensitivity to chlorhexidine or lidocaine. - Intended use only: apply exclusively to the urethra as directed. - Compromised urethral integrity: avoid if the urethral mucosa is severely damaged. - Monitor for allergic signs: discontinue if rash, swelling, or breathing difficulty occurs. - Store at room temperature: keep in the original container, protect from light and moisture.

What does Chlorhexidine Gluconate, Lidocaine Hydrochloride interact with?

Instillagel may interact with other medications or products.

Major Interactions (Avoid): - Concurrent use of other topical anesthetics: may cause additive local toxicity. - Simultaneous application of additional chlorhexidine‑containing products: increases risk of irritation.

Moderate Interactions (Monitor Closely): - Use with catheters impregnated with other antimicrobials: may alter efficacy. - Concomitant systemic steroids or wound‑healing agents: could affect local tissue response. - Combination with other local antiseptics: may increase irritation or chemical injury risk.

Frequently asked questions

What is Instillagel used for?+
Instillagel is a sterile gel containing chlorhexidine gluconate and lidocaine hydrochloride that is applied to the urethra before catheter insertion. It helps prevent urinary tract infections by providing antiseptic action and reduces discomfort by delivering local anaesthesia during catheterisation procedures.
How does chlorhexidine gluconate work in Instillagel?+
Chlorhexidine gluconate acts as a broad‑spectrum antiseptic by binding to bacterial cell walls and disrupting membrane integrity, leading to leakage of intracellular contents and cell death. This antimicrobial activity reduces bacterial colonisation of the urethra during catheter use.
What is the usual dose of Instillagel?+
The specific amount of Instillagel to be instilled into the urethra is determined by the prescribing clinician based on the procedure and patient needs. The prescriber will specify the volume to be administered immediately before catheter insertion.
Is Instillagel safe to use during pregnancy or breastfeeding?+
Safety data for Instillagel in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any potential risk to the mother or infant, and the decision should be made by a qualified healthcare professional.
How do I order Instillagel from GNH USA?+
To order Instillagel, submit an enquiry on the product page at gnh-usa.com, providing the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then replies with pricing, availability, shipping details and any necessary import documentation.
How does Instillagel compare with other catheter lubricants?+
Unlike simple lubricants, Instillagel combines an antiseptic (chlorhexidine) with a local anaesthetic (lidocaine), offering both infection control and pain relief. Conventional lubricants provide only friction reduction, so Instillagel may provide added clinical benefits in preventing catheter‑associated infections and improving patient comfort.
How should Instillagel be stored and handled?+
Instillagel should be stored at room temperature, preferably below 25 °C, in its original sealed container. Protect the gel from direct sunlight, excessive heat and moisture. Do not freeze or expose it to extreme temperatures, and keep it out of reach of children.
How is Instillagel administered?+
Instillagel is administered by a healthcare professional who instills a prescribed volume of the gel directly into the urethra using a sterile applicator or catheter lumen, typically immediately before catheter insertion. The gel spreads along the urethral mucosa to provide antiseptic and analgesic effects.
What are the most serious risks associated with Instillagel?+
The most serious risks include severe allergic reactions such as anaphylaxis, significant urethral inflammation or chemical cystitis, and rare cases of tissue necrosis. Immediate medical attention is required if signs of a severe reaction, such as difficulty breathing, swelling, or intense pain, occur.
Who should not use Instillagel?+
Instillagel should not be used in individuals with a known hypersensitivity to chlorhexidine, lidocaine, or any component of the formulation. It is also contraindicated in patients with severe urethral injury or ulceration where the gel could exacerbate tissue damage.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Chlorhexidine Gluconate, Lidocaine Hydrochloride
Route
Urethral Use
Manufacturer
Melisana Nv
Origin
EU

Related products