GNH USA

Europe — EMA

Innovair Nexthaler

GNH USA supplies Innovair Nexthaler (Beclometasone/Formoterol), a inhaled corticosteroid/long‑acting beta2‑agonist for asthma and COPD maintenance therapy.

Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous

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What is Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous?

Beclometasone dipropionate / Formoterol fumarate, the active ingredient in Innovair Nexthaler, is an inhaled corticosteroid/long‑acting beta2‑agonist combination presented as a dry powder inhaler for inhalation use. It provides maintenance therapy for asthma and chronic obstructive pulmonary disease in adults and adolescents.

GNH USA supplies Innovair Nexthaler as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous used for?

Innovair Nexthaler is used in the respiratory disease pathway to provide long‑term control of airway obstruction.

- Asthma: reduces symptoms, improves lung function and lowers the risk of exacerbations in patients with persistent asthma. - COPD: improves airflow, decreases symptom burden and helps prevent COPD exacerbations. - Chronic bronchitis (as part of COPD): maintains airway patency and reduces cough frequency.

What are the side effects of Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous?

Common Side Effects: - Throat irritation or soreness - Hoarseness of voice - Oral candidiasis (thrush) - Cough or wheeze after inhalation - Headache - Tremor or shakiness

Serious or Rare Side Effects: - Paradoxical bronchospasm - Severe allergic reaction (anaphylaxis) - Cardiovascular events such as tachycardia or arrhythmia - Hypokalemia (low blood potassium) - Hyperglycemia in diabetic patients

What precautions apply to Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous?

Precautions should be observed when prescribing Innovair Nexthaler. - Assess infection risk: monitor for respiratory infections before and during therapy. - Oral hygiene: rinse mouth after each inhalation to reduce candidiasis. - Cardiovascular caution: use carefully in patients with known heart disease or arrhythmias. - Avoid abrupt discontinuation: taper under medical supervision to prevent loss of control. - Hypersensitivity: discontinue if signs of allergic reaction appear. - Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

What does Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous interact with?

Potential drug interactions must be considered.

Major Interactions (Avoid): - Non‑selective beta‑blockers: may diminish bronchodilator effect and precipitate bronchospasm. - Strong CYP3A4 inhibitors (e.g., ketoconazole): can increase systemic steroid exposure.

Moderate Interactions (Monitor Closely): - Diuretics: may exacerbate hypokalemia when combined with beta2‑agonists. - Other inhaled corticosteroids: increase risk of systemic effects. - CYP3A4 inducers (e.g., rifampicin): may reduce steroid efficacy. - Anticholinergic bronchodilators: monitor for additive anticholinergic effects.

Frequently asked questions

What is Innovair Nexthaler used for?+
Innovair Nexthaler is a prescription dry‑powder inhaler that provides maintenance therapy for asthma and chronic obstructive pulmonary disease (COPD). It combines an inhaled corticosteroid with a long‑acting beta2‑agonist to reduce airway inflammation and keep the airways open over the long term.
How does the combination of beclometasone and formoterol work?+
Beclometasone acts on glucocorticoid receptors in airway cells, suppressing inflammatory pathways and decreasing swelling. Formoterol binds to beta2‑adrenergic receptors on airway smooth muscle, raising cyclic AMP levels and producing sustained bronchodilation. Together they control inflammation while maintaining airway patency.
What is the usual dose of Innovair Nexthaler?+
The prescribed dose of Innovair Nexthaler is determined by the treating physician based on the patient’s age, disease severity, and response to therapy. The prescriber will instruct the patient on the number of inhalations per day and the timing of each dose.
Is Innovair Nexthaler safe to use during pregnancy or breastfeeding?+
Safety data for Innovair Nexthaler in pregnancy and lactation are limited. The decision to use it should be made by a healthcare professional after weighing the potential benefits for the mother against any possible risks to the fetus or infant.
How do I order Innovair Nexthaler from GNH USA?+
To order Innovair Nexthaler, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Innovair Nexthaler compare with other asthma inhalers?+
Innovair Nexthaler combines a corticosteroid and a long‑acting beta2‑agonist in a dry‑powder device, offering once‑daily dosing for many patients. Compared with separate inhalers or combination products that use metered‑dose sprays, it may provide more consistent dosing and eliminates the need for propellants, though device preference varies by individual.
What are the storage and handling requirements for Innovair Nexthaler?+
Store Innovair Nexthaler at room temperature, below 25 °C, in its original packaging. Keep the device away from moisture and direct sunlight. Do not expose it to extreme heat or freeze it, as this could affect the powder’s integrity and dosing performance.
How is Innovair Nexthaler administered?+
The patient inhales the powder through the mouthpiece of the Nexthaler device after a full exhalation, then holds their breath for several seconds to allow the medication to reach the lungs. The inhaler should be primed according to the manufacturer’s instructions before first use.
What are the most serious risks associated with Innovair Nexthaler?+
Serious risks include paradoxical bronchospasm, severe allergic reactions such as anaphylaxis, cardiovascular events like tachycardia or arrhythmia, and systemic effects from the corticosteroid component such as hyperglycemia or adrenal suppression, especially with high‑dose or prolonged use.
Who should not use Innovair Nexthaler?+
Innovair Nexthaler should be avoided in patients with known hypersensitivity to beclometasone, formoterol, or any excipients in the inhaler. It is also contraindicated in individuals who experience severe paradoxical bronchospasm after inhalation or who have uncontrolled cardiovascular disease without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous
Route
Inhalation Use
Manufacturer
Chiesi Farmaceutici S.P.A.
Origin
EU

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