GNH USA

Europe — EMA

Innovair Nexthaler

GNH USA supplies Innovair Nexthaler (Formoterol/Beclometasone), a combination inhaled corticosteroid/long‑acting β2‑agonist for asthma and COPD maintenance

Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous

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What is Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous?

Formoterol fumarate and beclometasone dipropionate, the active ingredients in Innovair Nexthaler, are a combination inhaled corticosteroid/long‑acting β2‑agonist presented as a dry‑powder inhaler for inhalation use. They are indicated for maintenance therapy to control symptoms and reduce exacerbations in adults with asthma or chronic obstructive pulmonary disease (COPD). GNH USA supplies Innovair Nexthaler as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides reliable logistics through its network for global customers.

What is Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous used for?

Innovair Nexthaler, a combination inhaled corticosteroid and long‑acting β2‑agonist, is used in the respiratory disease pathway for maintenance therapy.

- Asthma: improves symptom control and reduces the frequency of exacerbations. - COPD: maintains lung function and decreases the risk of flare‑ups. - Chronic respiratory disease with reversible airway obstruction: provides long‑term bronchodilation and anti‑inflammatory effect.

What are the side effects of Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous?

Common Side Effects: - Throat irritation or soreness. - Hoarseness or voice changes. - Oral candidiasis (thrush) after use. - Cough or wheezing immediately after inhalation. - Headache. - Tremor or mild palpitations.

Serious or Rare Side Effects: - Paradoxical bronchospasm requiring immediate medical attention. - Severe allergic reaction such as anaphylaxis. - Cardiac arrhythmias or significant tachycardia. - Hypokalemia, especially with high doses. - Cataracts or glaucoma with prolonged use. - Osteoporosis or adrenal suppression with chronic systemic exposure.

What precautions apply to Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous?

Before prescribing Innovair Nexthaler, consider the following precautions: - Assess inhaler technique: ensure the patient can use the dry‑powder inhaler correctly. - Monitor for oral candidiasis: advise rinsing the mouth with water after each dose. - Screen for cardiovascular disease: use cautiously in patients with arrhythmias or ischemic heart disease. - Avoid use for acute bronchospasm: provide a rescue inhaler for sudden symptoms. - Pregnancy and lactation: prescribe only if the potential benefit justifies the potential risk. - Store at ambient temperature: keep below 25 °C, protect from moisture and keep in the original packaging.

What does Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous interact with?

Innovair Nexthaler may interact with other medicines as follows:

Major Interactions (Avoid): - Beta‑blockers: can diminish the bronchodilator effect of formoterol. - Potent CYP3A4 inhibitors (e.g., ketoconazole): may increase systemic exposure to beclometasone.

Moderate Interactions (Monitor Closely): - Diuretics: may exacerbate hypokalemia when combined with a β2‑agonist. - Theophylline: concurrent use can increase the risk of tachycardia and tremor. - Other inhaled corticosteroids: combined use may raise the risk of systemic corticosteroid effects.

Frequently asked questions

What is Innovair Nexthaler used for?+
Innovair Nexthaler is a combination inhaled corticosteroid and long‑acting β2‑agonist indicated for maintenance therapy in adults with asthma or chronic obstructive pulmonary disease (COPD). It helps control daily symptoms, improves lung function, and reduces the frequency and severity of disease exacerbations when used regularly as prescribed.
How does formoterol fumarate work?+
Formoterol fumarate is a long‑acting β2‑adrenergic agonist that binds to β2 receptors on airway smooth muscle cells. This binding activates adenylate cyclase, increasing cyclic AMP levels, which leads to relaxation of the smooth muscle and sustained bronchodilation, helping keep the airways open for several hours after inhalation.
What is the usual dose of Innovair Nexthaler?+
The dose of Innovair Nexthaler is determined by the prescribing clinician based on the individual’s disease severity, response to therapy, and clinical guidelines. The prescriber will specify the number of inhalations to be taken each day, typically one or two inhalations, and may adjust the regimen during follow‑up visits.
Is Innovair Nexthaler safe to use during pregnancy or breastfeeding?+
Safety data for Innovair Nexthaler in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers should discuss the risks and benefits with the patient and consider alternative therapies when appropriate.
How do I order Innovair Nexthaler from GNH USA?+
To order Innovair Nexthaler, submit an enquiry on the product page at gnh-usa.com, indicating the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide. After the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements), and assist with import documentation.
How does Innovair Nexthaler compare with other combination inhalers?+
Innovair Nexthaler combines formoterol, a long‑acting β2‑agonist, with beclometasone, an inhaled corticosteroid, similar to other LABA/ICS products such as Symbicort or Budesonide/Formoterol. Its dry‑powder inhaler format may offer a breath‑actuated delivery that does not require propellants, which some patients prefer. Clinical efficacy and safety are comparable when used according to guideline‑based dosing.
How should Innovair Nexthaler be stored and handled?+
Innovair Nexthaler should be stored at ambient temperature, below 25 °C, in a dry environment. Keep the device in its original packaging to protect it from moisture and humidity. Do not expose the inhaler to extreme heat or direct sunlight, and keep it out of reach of children.
How is Innovair Nexthaler administered?+
To use Innovair Nexthaler, the patient should first open the mouthpiece, exhale fully away from the device, then place the inhaler between the lips and inhale sharply and deeply through the mouth. Hold the breath for a few seconds, then exhale slowly. Rinse the mouth with water after each use to reduce the risk of oral candidiasis.
What are the most serious risks associated with Innovair Nexthaler?+
Serious risks include paradoxical bronchospasm, which can worsen breathing and requires immediate medical attention, and severe allergic reactions such as anaphylaxis. Cardiovascular events like significant tachycardia, arrhythmias, and hypokalemia may also occur, especially at higher doses or in susceptible individuals. Regular monitoring and prompt reporting of symptoms are essential.
Who should not use Innovair Nexthaler?+
Innovair Nexthaler is contraindicated in patients with a known hypersensitivity to formoterol, beclometasone, or any excipients in the inhaler. It should not be used for the relief of acute bronchospasm. Caution is advised in individuals with severe cardiovascular disorders, uncontrolled hypertension, or a history of paradoxical bronchospasm.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Formoterol Fumarate Dihydrate, Beclometasone Dipropionate Anhydrous
Route
Inhalation Use
Manufacturer
Chiesi S.A.S.
Origin
EU

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