GNH USA

Europe — EMA

Innovair

GNH USA supplies Innovair (Beclometasone/Formoterol), a inhaled corticosteroid/long‑acting β2‑agonist for asthma and COPD maintenance therapy.

Beclometasone Dipropionate, Formoterol Fumarate Dihydrate

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What is Beclometasone Dipropionate, Formoterol Fumarate Dihydrate?

Beclometasone dipropionate, the active ingredient in Innovair, is a inhaled corticosteroid/long‑acting β2‑agonist combination presented as an inhalation aerosol for inhalation use. The formulation delivers both anti‑inflammatory and bronchodilator actions, helping to control airway symptoms and reduce exacerbations in patients with asthma and chronic obstructive pulmonary disease (COPD).

GNH USA supplies Innovair as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality‑assured product availability and regulatory compliance across multiple markets. The company provides reliable logistics and technical support for seamless integration into therapeutic formularies.

What is Beclometasone Dipropionate, Formoterol Fumarate Dihydrate used for?

Innovair is used as a maintenance inhaler targeting airway inflammation and bronchoconstriction in chronic respiratory diseases. - Asthma: provides long‑term control of symptoms and reduces the frequency of exacerbations. - Chronic obstructive pulmonary disease (COPD): improves lung function and helps prevent worsening of disease.

What are the side effects of Beclometasone Dipropionate, Formoterol Fumarate Dihydrate?

The most frequently reported adverse reactions with Innovair involve the respiratory tract and systemic effects of the corticosteroid and β2‑agonist components.

Common Side Effects: - Throat irritation or hoarseness - Oral candidiasis (thrush) - Cough or wheeze after inhalation - Headache - Tremor or shakiness - Palpitations

Serious or Rare Side Effects: - Paradoxical bronchospasm - Adrenal suppression with prolonged high‑dose use - Severe allergic reactions (anaphylaxis, angioedema) - Cardiac arrhythmias or tachycardia - Hypokalemia - Increased risk of pneumonia in COPD patients

What precautions apply to Beclometasone Dipropionate, Formoterol Fumarate Dihydrate?

Before prescribing Innovair, clinicians should consider several precautionary measures to ensure safe and effective use. - Assess inhaler technique: confirm patient can use the device correctly to maximize drug delivery. - Monitor for oral thrush: advise rinsing mouth after each use. - Evaluate cardiovascular status: use caution in patients with arrhythmias or severe hypertension. - Use the lowest effective dose: adjust based on symptom control and side‑effect profile. - Review concomitant medications: especially beta‑blockers and strong CYP3A4 inhibitors. - Store at ambient temperature: keep the inhaler in the original container, protect from moisture and heat.

What does Beclometasone Dipropionate, Formoterol Fumarate Dihydrate interact with?

Innovair may interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase systemic corticosteroid exposure. - Non‑selective β‑blockers: can diminish bronchodilator response and precipitate bronchospasm. - Diuretics (loop or thiazide): may exacerbate hypokalemia when combined with formoterol.

Moderate Interactions (Monitor Closely): - Other inhaled corticosteroids or LABAs: additive systemic effects may require dose adjustment. - Anticholinergic bronchodilators: monitor for excessive bronchodilation. - MAO inhibitors or tricyclic antidepressants: may increase risk of tachycardia. - Theophylline: possible enhanced stimulant effects on the heart.

Frequently asked questions

What conditions is Innovair used to treat?+
Innovair is prescribed as a maintenance inhaler for patients with asthma and chronic obstructive pulmonary disease (COPD). It helps control chronic airway inflammation and provides long‑acting bronchodilation to reduce symptoms and prevent disease exacerbations.
How does beclometasone dipropionate work in Innovair?+
Beclometasone dipropionate binds to glucocorticoid receptors in airway cells, altering gene expression to suppress inflammatory cytokines, reduce edema, and limit immune cell activation. This anti‑inflammatory effect lowers airway hyper‑responsiveness and mucus production.
What determines the dose of Innovair?+
The dose of Innovair is individualized by the prescribing healthcare professional based on the severity of asthma or COPD, patient response, and safety considerations. Patients should follow the prescriber’s instructions and not adjust the dose on their own.
Is Innovair safe to use during pregnancy or while breastfeeding?+
Data on the use of beclometasone/formoterol during pregnancy and lactation are limited. The medication should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified clinician.
How do I order Innovair from GNH USA?+
To request Innovair, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Innovair compare with other maintenance inhalers such as Symbicort?+
Innovair and other combination inhalers like Symbicort contain the same classes of drugs—a corticosteroid and a long‑acting β2‑agonist. Differences may lie in device design, specific salt forms, or approved dosing strengths, but both aim to provide anti‑inflammatory and bronchodilator effects for asthma and COPD maintenance.
What are the recommended storage conditions for Innovair?+
Innovair should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the inhaler away from moisture, direct sunlight, and extreme heat to maintain drug stability and device performance.
How should Innovair be administered?+
Innovair is delivered via inhalation. The patient should shake the inhaler, exhale fully, place the mouthpiece in the mouth, and inhale slowly and deeply while actuating the device. After each dose, rinse the mouth with water and spit to reduce the risk of oral thrush.
What are the most serious risks associated with Innovair?+
Serious risks include paradoxical bronchospasm, adrenal suppression with prolonged high‑dose use, severe allergic reactions such as anaphylaxis, cardiac arrhythmias, hypokalemia, and an increased risk of pneumonia in patients with COPD. Patients should be monitored for these events.
Who should not use Innovair?+
Innovair is contraindicated in individuals with known hypersensitivity to beclometasone, formoterol, or any component of the inhaler. It should also be avoided in patients who have experienced a severe paradoxical bronchospasm after using a similar medication.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Beclometasone Dipropionate, Formoterol Fumarate Dihydrate
Route
Inhalation Use
Manufacturer
Chiesi Farmaceutici S.P.A.
Origin
EU

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