GNH USA

Europe — EMA

Inflanor

GNH USA supplies Inflanor (Ibuprofen), a nonsteroidal anti-inflammatory drug for mild to moderate pain, fever and arthritis.

Ibuprofen

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What is Ibuprofen?

Ibuprofen, the active ingredient in Inflanor, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It provides analgesic, antipyretic, and anti‑inflammatory effects for mild to moderate pain, fever, and inflammatory conditions such as arthritis, primarily in adult patients.

GNH USA supplies Inflanor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards, reliable global distribution, regulatory compliance and batch traceability.

What is Ibuprofen used for?

Inflanor (ibuprofen) is indicated for conditions involving pain, fever, or inflammation within the musculoskeletal and systemic disease families.

- Mild to moderate pain: Provides analgesic relief for headaches, dental pain, menstrual cramps, and musculoskeletal discomfort. - Fever: Reduces elevated body temperature associated with infections or inflammatory processes. - Inflammatory conditions such as arthritis: Decreases joint swelling and improves mobility in osteoarthritis and rheumatoid arthritis.

What are the side effects of Ibuprofen?

Ibuprofen may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort. - Headache: mild to moderate intensity. - Dizziness or vertigo. - Skin rash or mild itching.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulcer perforation. - Acute renal impairment or worsening of chronic kidney disease. - Severe allergic reactions including anaphylaxis. - Hepatotoxicity or elevated liver enzymes. - Thrombocytopenia or other hematologic abnormalities. - Cardiovascular events such as myocardial infarction or stroke in high‑risk patients.

What precautions apply to Ibuprofen?

Before initiating therapy, consider patient‑specific risk factors and monitor appropriately.

- Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding. - Monitor renal function: use caution in those with impaired kidney function or dehydration. - Use the lowest effective dose for the shortest duration needed. - Avoid in individuals with known hypersensitivity to ibuprofen or other NSAIDs. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

What does Ibuprofen interact with?

Ibuprofen can interact with several drug classes, requiring careful management.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Systemic corticosteroids: heightened risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal perfusion, especially in volume‑depleted patients. - Diuretics: potential for reduced efficacy and renal impairment. - Lithium: ibuprofen can raise lithium serum levels. - Methotrexate: may decrease clearance, increasing toxicity.

Frequently asked questions

What is Inflanor used for?+
Inflanor contains ibuprofen, an NSAID that is used to relieve mild to moderate pain, reduce fever, and decrease inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, dental pain, headache, and menstrual cramps. It is prescribed for adult patients when a non‑opioid analgesic and antipyretic are appropriate.
How does ibuprofen work?+
Ibuprofen works by inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for the synthesis of prostaglandins. By lowering prostaglandin levels, it reduces inflammation, diminishes pain signaling, and helps reset the hypothalamic temperature set‑point, thereby providing analgesic, antipyretic, and anti‑inflammatory effects.
What is the usual dose of Inflanor?+
The dose of Inflanor is determined by the prescribing healthcare professional based on the individual’s condition, age, weight, and overall health status. The prescriber will select the appropriate strength, frequency, and duration to achieve therapeutic benefit while minimizing risk.
Is Inflanor safe during pregnancy or breastfeeding?+
Safety of ibuprofen in pregnancy and lactation has not been fully established. It should only be used when the potential benefit justifies the potential risk to the fetus or infant, and only under medical supervision. Women who are pregnant, especially in the third trimester, or who are breastfeeding should discuss alternatives with their healthcare provider.
How do I order Inflanor from GNH USA?+
To place an order, submit an enquiry on the Inflanor product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials. After verification, the sales team provides pricing, availability, shipping details (including any cold‑chain requirements if applicable), and assists with import documentation.
How does Inflanor compare with other NSAIDs?+
Inflanor (ibuprofen) shares the core NSAID properties of analgesia, antipyresis, and anti‑inflammation with agents such as naproxen, diclofenac, and aspirin. Compared with some longer‑acting NSAIDs, ibuprofen has a relatively short half‑life, allowing flexible dosing but may require multiple daily administrations. Its safety profile is well‑characterized, though gastrointestinal and renal risks are comparable across the class.
How should Inflanor be stored and handled?+
Inflanor should be stored at room temperature, below 25 °C, in its original container to protect it from moisture and direct sunlight. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.
How is Inflanor administered?+
Inflanor is taken orally with a full glass of water. It may be taken with or without food; however, taking it with food or milk can reduce the likelihood of gastrointestinal discomfort. Swallow tablets whole; do not crush or chew unless specifically instructed by a healthcare professional.
What are the most serious risks associated with Inflanor?+
The most serious risks include gastrointestinal bleeding or ulcer perforation, acute kidney injury, severe allergic reactions such as anaphylaxis, and increased cardiovascular events (e.g., heart attack or stroke) especially in patients with existing heart disease. Patients should seek immediate medical attention if they experience signs of bleeding, severe abdominal pain, sudden swelling, or difficulty breathing.
Who should not use Inflanor?+
Inflanor should be avoided in individuals with known hypersensitivity to ibuprofen or any NSAID, active gastrointestinal ulcer or bleeding, severe renal or hepatic impairment, the third trimester of pregnancy, and patients concurrently using anticoagulants without close monitoring. Consultation with a healthcare professional is essential before starting therapy in these situations.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ibuprofen
Route
Oral Use
Manufacturer
Zentiva, K.S.
Origin
EU

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