Europe — EMA
Infectosupramox Saft (Amoxicillin Trihydrate, Potassium Clavulanate)
GNH USA supplies Infectosupramox Saft (Amoxicillin Trihydrate and Potassium Clavulanate), a penicillin beta‑lactam antibiotic for acute sinusitis, otitis
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What is Amoxicillin Trihydrate, Potassium Clavulanate?
Amoxicillin Trihydrate and Potassium Clavulanate, the active ingredient in Infectosupramox Saft, is a penicillin beta‑lactam antibiotic presented as a syrup for oral use. It treats a range of bacterial infections such as acute sinusitis, otitis media, community‑acquired pneumonia, urinary tract infections and skin and soft‑tissue infections in both adults and children.
GNH USA supplies Infectosupramox Saft as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Amoxicillin Trihydrate, Potassium Clavulanate used for?
Infectosupramox Saft, a combination penicillin antibiotic, is used to treat bacterial infections of the respiratory, urinary and skin systems.
- Acute sinusitis: clears the sinus infection and reduces nasal congestion. - Acute otitis media: eradicates the causative bacteria and improves hearing. - Community‑acquired pneumonia: eliminates pulmonary pathogens and prevents complications. - Urinary tract infections: removes uropathogens and relieves dysuria. - Skin and soft‑tissue infections: treats cellulitis and other bacterial skin conditions.
What are the side effects of Amoxicillin Trihydrate, Potassium Clavulanate?
Infectosupramox Saft may cause adverse reactions that vary in frequency and severity.
Common Side Effects: - Diarrhea: mild to moderate loose stools. - Nausea: feeling of queasiness, often transient. - Rash: skin erythema or maculopapular eruption. - Taste disturbance: altered or metallic taste.
Serious or Rare Side Effects: - Anaphylaxis: severe, potentially life‑threatening allergic reaction. - Clostridioides difficile‑associated colitis: severe diarrhea with abdominal pain. - Liver enzyme elevation: increased ALT/AST indicating hepatic stress.
What precautions apply to Amoxicillin Trihydrate, Potassium Clavulanate?
Before prescribing Infectosupramox Saft, consider the following precautions.
- Allergy assessment: confirm no known hypersensitivity to penicillins or β‑lactamase inhibitors. - Renal function: adjust dose in patients with impaired renal clearance. - Hepatic monitoring: perform liver function tests during prolonged therapy. - Pregnancy and lactation: use only if the potential benefit justifies the potential risk. - Store at ambient temperature: keep below 25°C, retain in the original container, and protect from moisture.
What does Amoxicillin Trihydrate, Potassium Clavulanate interact with?
Infectosupramox Saft can interact with several medicines; some require avoidance while others need close monitoring.
Major Interactions (Avoid): - Allopurinol: increased risk of severe skin reactions. - Methotrexate: heightened methotrexate toxicity. - Oral contraceptives: reduced hormonal efficacy, risk of breakthrough bleeding. - Warfarin: enhanced anticoagulant effect, monitor INR closely.
Moderate Interactions (Monitor Closely): - Probenecid: may raise amoxicillin plasma concentrations. - Antacids containing aluminum or magnesium: can decrease absorption of amoxicillin. - Carbapenems (e.g., imipenem): antagonistic effect, may diminish antibacterial activity.



