Infanrix-Polio

Poliovirus (inactivated) type 3, the active ingredient in Infanrix-Polio, is a vaccine presented as a vaccine for intramuscular use. It induces immunity against poliovirus type 3 and pertussis in infants and children.

GNH USA supplies Infanrix-Polio as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Infanrix-Polio is a combination vaccine that protects against viral and bacterial respiratory infections in the pediatric population. - Poliomyelitis (type 3): prevents infection caused by poliovirus type 3. - Pertussis (whooping cough): prevents disease caused by Bordetella pertussis. - Childhood immunisation schedule: provides scheduled protection as part of routine infant vaccination programmes.

Common Side Effects: - Injection site pain: mild to moderate discomfort at the site of administration. - Redness or swelling: localized erythema or edema. - Low‑grade fever: transient temperature rise within 24‑48 hours. - Irritability or crying: especially in infants. - Loss of appetite: temporary decrease in feeding. - Fatigue: mild tiredness after vaccination.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical attention. - Seizures: febrile or non‑febrile convulsions. - High fever (>40 °C): may indicate a systemic reaction. - Prolonged crying (>3 hours): possible sign of distress. - Hypotonic‑hyporesponsive episode: rare neurological event. - Severe local reaction: necrosis or ulceration at injection site.

Infanrix-Polio should be administered after careful assessment of the individual’s health status. - Allergy assessment: verify no severe allergy to any vaccine component. - Immunocompromised patients: evaluate risk‑benefit before use. - Acute illness: postpone vaccination if the child has a moderate or severe febrile illness. - Previous vaccine reaction: consider deferral if a serious adverse event occurred after a prior dose. - Pregnancy: consult a healthcare professional before administration to pregnant women. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Vaccination may be influenced by concurrent therapies or other vaccines. Major Interactions (Avoid): - Live oral polio vaccine: avoid simultaneous administration due to interference. - Immunoglobulin or blood products: may neutralise vaccine antigens. Moderate Interactions (Monitor Closely): - Systemic corticosteroids: may reduce immunogenic response. - Antipyretics (e.g., acetaminophen): can mask fever, monitor for underlying reactions. - Other injectable vaccines: schedule at different sites or times to minimise local reactogenicity.