GNH USA

Europe — EMA

Indocollyre

GNH USA supplies Indocollyre (Indometacin), an anti‑inflammatory eye drop for ocular inflammation and anterior uveitis. Request a quote for global supply.

Indometacin

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What is Indometacin?

Indometacin, the active ingredient in Indocollyre, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an ophthalmic solution for ocular use. It reduces inflammation and pain in various eye conditions, particularly after surgery or in inflammatory eye diseases.

GNH USA supplies Indocollyre as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with comprehensive regulatory support and reliable global delivery.

What is Indometacin used for?

Indometacin ophthalmic solution is employed to manage inflammatory conditions of the eye. - Postoperative ocular inflammation: reduces swelling and pain following eye surgery. - Anterior uveitis: helps control inflammation of the anterior segment of the eye. - Allergic conjunctivitis: alleviates inflammatory symptoms associated with allergic eye reactions. - Keratitis: diminishes inflammation of the cornea in certain infectious or non‑infectious cases.

What are the side effects of Indometacin?

Indometacin eye drops may cause local and systemic adverse reactions, which are categorized by frequency and severity.

Common Side Effects: - Burning or stinging sensation: transient discomfort upon instillation. - Redness of the conjunctiva: mild ocular irritation. - Tearing: increased lacrimation after use. - Blurred vision: temporary visual disturbance.

Serious or Rare Side Effects: - Corneal ulceration: breakdown of corneal epithelium. - Keratitis: inflammation of the cornea that may impair vision. - Severe allergic reaction: swelling, rash, or anaphylaxis.

What precautions apply to Indometacin?

When using Indocollyre, consider the following precautions. - Hypersensitivity: avoid use in patients with known allergy to indometacin or other NSAIDs. - Corneal disease: use with caution in existing corneal ulcers or keratitis. - Contact lens wearers: discontinue lenses during treatment to prevent irritation. - Concurrent ocular NSAIDs: avoid using multiple NSAID eye drops simultaneously. - Systemic NSAID therapy: monitor for additive systemic effects if the patient is on oral NSAIDs. - Store at room temperature: keep in the original container, protect from light and moisture.

What does Indometacin interact with?

Indometacin eye drops can interact with other medicines; awareness of major and moderate interactions helps ensure safety.

Major Interactions (Avoid): - Systemic anticoagulants (e.g., warfarin): increased risk of bleeding. - Oral or parenteral NSAIDs: additive gastrointestinal and renal toxicity. - Corticosteroid eye drops: heightened risk of corneal thinning.

Moderate Interactions (Monitor Closely): - Systemic corticosteroids: monitor for delayed wound healing. - Other ocular medications (e.g., mydriatics): assess for altered intra‑ocular pressure. - Antihypertensive agents: watch for potential fluid retention.

Frequently asked questions

What is Indocollyre used for?+
Indocollyre is an ophthalmic solution containing indometacin that is used to treat inflammatory eye conditions such as postoperative ocular inflammation, anterior uveitis, allergic conjunctivitis, and certain forms of keratitis. It helps reduce pain, swelling, and redness in the affected eye.
How does indometacin work in the eye?+
Indometacin works by non‑selectively inhibiting cyclooxygenase‑1 and cyclooxygenase‑2 enzymes in ocular tissues. This blocks the formation of prostaglandins, which are key mediators of inflammation, thereby decreasing vascular permeability, leukocyte migration, and the overall inflammatory response within the eye.
What is the usual dose of Indocollyre?+
The dosing regimen for Indocollyre is determined by the prescribing eye‑care professional based on the specific condition, severity, and patient factors. The prescriber will provide instructions on the number of drops, frequency, and duration of treatment.
Is Indocollyre safe to use during pregnancy or breastfeeding?+
Safety data for indometacin ophthalmic use in pregnancy or while breastfeeding are limited. Healthcare providers should evaluate the potential benefits against any possible risks and discuss alternative options if appropriate.
How do I order Indocollyre from GNH USA?+
To order Indocollyre, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.
How does Indocollyre compare with other ocular NSAIDs?+
Indocollyre contains indometacin, a non‑selective NSAID, which offers broad prostaglandin inhibition. Compared with selective COX‑2 ocular agents, indometacin may provide stronger anti‑inflammatory effects but can carry a slightly higher risk of corneal irritation. Choice of agent depends on the clinical scenario and physician preference.
How should Indocollyre be stored and handled?+
Indocollyre should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed when not in use and retain it in its original packaging to protect the formulation from contamination.
How is Indocollyre administered?+
The solution is applied topically to the affected eye(s) as directed by the prescriber. Typically, a few drops are placed into the conjunctival sac, avoiding contact with the eyelid or eyelashes, and the patient should blink gently to spread the medication.
What are the most serious risks associated with Indocollyre?+
Serious risks include corneal ulceration, keratitis, and severe allergic reactions such as swelling, rash, or anaphylaxis. If any of these occur, the patient should discontinue use immediately and seek medical attention.
Who should not use Indocollyre?+
Indocollyre should not be used by individuals with a known hypersensitivity to indometacin, other NSAIDs, or any component of the formulation. Patients with active corneal ulcers, severe keratitis, or uncontrolled intra‑ocular pressure should also avoid its use unless specifically directed by an eye‑care specialist.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Indometacin
Route
Ocular Use
Manufacturer
Bausch + Lomb Ireland Limited
Origin
EU

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