GNH USA

Europe — EMA

Inderal

GNH USA supplies Inderal (Propranolol), a beta blocker for hypertension, angina, cardiac arrhythmias and migraine prophylaxis.

Propranolol Hydrochloride

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What is Propranolol Hydrochloride?

Propranolol, the active ingredient in Inderal, is a beta blocker presented as an oral tablet for systemic use. It reduces heart rate and blood pressure and is employed in the management of hypertension, angina, cardiac arrhythmias, myocardial infarction prophylaxis, migraine prevention, and essential tremor.

GNH USA supplies Inderal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable quality and regulatory compliance for global markets, including Europe, Asia and Africa, and adhering to stringent pharmacopeial standards.

What is Propranolol Hydrochloride used for?

Inderal (propranolol) is a non‑selective beta‑adrenergic blocker used to manage several cardiovascular and neurologic conditions.

- Hypertension: lowers blood pressure and reduces cardiovascular risk. - Angina pectoris: decreases myocardial oxygen demand to relieve chest pain. - Cardiac arrhythmias: stabilises heart rhythm by slowing conduction. - Myocardial infarction prophylaxis: reduces the chance of recurrent heart attacks. - Migraine prophylaxis: prevents migraine attacks by modulating vascular tone. - Essential tremor: diminishes tremor amplitude in patients.

What are the side effects of Propranolol Hydrochloride?

Common Side Effects: - Fatigue or tiredness. - Dizziness or light‑headedness. - Cold hands and feet. - Nausea or stomach upset. - Sleep disturbances, including vivid dreams. - Mild depression.

Serious or Rare Side Effects: - Bradycardia or severe slowing of heart rate. - Marked hypotension. - Heart block or worsening arrhythmias. - Bronchospasm, especially in asthmatic patients. - Severe hypoglycaemia in diabetic individuals. - Allergic reactions such as rash, swelling, or anaphylaxis.

What precautions apply to Propranolol Hydrochloride?

Before starting Inderal, consider the following safety measures: - Cardiac assessment: evaluate heart rate, blood pressure, and conduction abnormalities. - Respiratory review: avoid use in uncontrolled asthma or severe chronic obstructive pulmonary disease. - Diabetes monitoring: watch for masking of hypoglycaemia symptoms. - Thyroid status: adjust dose in hyperthyroid patients. - Pregnancy and lactation: discuss risks with a healthcare professional. - Store at room temperature: keep in the original container, protect from moisture and light.

What does Propranolol Hydrochloride interact with?

Propranolol can interact with several medicines; monitoring is essential.

Major Interactions (Avoid): - Other beta‑blockers: additive bradycardia and hypotension. - Calcium channel blocker verapamil: risk of severe heart block. - Insulin or oral hypoglycaemic agents: may potentiate hypoglycaemia.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible enhanced blood pressure lowering. - Diuretics: may increase risk of electrolyte imbalance. - NSAIDs: can reduce antihypertensive effect of propranolol.

Frequently asked questions

What conditions is Inderal used for?+
Inderal, containing propranolol, is prescribed for high blood pressure, chest pain due to angina, various cardiac rhythm disorders, prevention of repeat heart attacks, migraine prevention, and essential tremor. It works across cardiovascular and neurologic pathways to control symptoms and reduce the risk of complications.
How does propranolol work in the body?+
Propranolol blocks both beta‑1 and beta‑2 adrenergic receptors, preventing natural stress hormones from stimulating the heart and blood vessels. This leads to a slower heart rate, reduced contractility, and lower blood pressure. In the brain, beta‑blockade helps stabilise neuronal activity, which contributes to migraine and tremor control.
What is the usual dose of Inderal?+
The specific dose of Inderal is determined by the prescribing clinician based on the individual’s medical condition, age, weight, and response to therapy. Patients should follow the dosage instructions provided by their healthcare professional and not adjust the amount without medical guidance.
Is Inderal safe during pregnancy or breastfeeding?+
Safety of propranolol during pregnancy or while nursing should be evaluated by a qualified healthcare provider. The drug may cross the placenta and enter breast milk, so a prescriber will weigh potential benefits against possible risks to the fetus or infant before recommending use.
How do I order Inderal from GNH USA?+
To request Inderal, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Inderal compare with other beta blockers?+
Inderal (propranolol) is a non‑selective beta‑blocker, meaning it blocks both beta‑1 and beta‑2 receptors, unlike cardio‑selective agents that primarily affect beta‑1. This broader activity can be advantageous for migraine and tremor but may require caution in patients with respiratory conditions where beta‑2 blockade could worsen symptoms.
What are the storage requirements for Inderal?+
Inderal should be stored at room temperature, ideally below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability throughout its shelf life.
How is Inderal administered?+
Inderal is taken orally, usually with a glass of water. Depending on the formulation, it may be swallowed whole or, if a tablet, can be split only if the prescribing information allows. Patients should follow the timing and food instructions given by their prescriber.
What are the most serious risks associated with Inderal?+
The most serious risks include severe bradycardia, marked hypotension, heart block, bronchospasm in patients with asthma or COPD, and masking of hypoglycaemia symptoms in diabetics. Any sudden chest pain, fainting, or difficulty breathing should prompt immediate medical attention.
Who should not use Inderal?+
Inderal is contraindicated in individuals with known hypersensitivity to propranolol, severe bradycardia, second‑ or third‑degree heart block without a pacemaker, uncontrolled asthma, and certain types of heart failure. Patients with these conditions should discuss alternative therapies with their healthcare provider.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Propranolol Hydrochloride
Route
Oral Use
Manufacturer
Atnahs Pharma Netherlands B.V.
Origin
EU

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