Indapamide Sr Pliva

Indapamide, the active ingredient in Indapamide Sr Pliva, is a thiazide-like diuretic presented as a tablet for oral use. It is used to treat hypertension and edema associated with congestive heart failure in adult patients.

GNH USA supplies Indapamide Sr Pliva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Indapamide is a thiazide‑like diuretic used to manage conditions related to fluid overload and high blood pressure.

Hypertension: lowers systolic and diastolic blood pressure, reducing cardiovascular risk. Edema associated with congestive heart failure: promotes diuresis to reduce fluid accumulation. Adjunct in resistant hypertension: assists in blood pressure reduction when combined with other antihypertensive agents.

Indapamide may cause a range of adverse reactions, from mild to serious.

Common Side Effects: - Dizziness or light‑headedness - Headache - Increased frequency of urination - Electrolyte imbalance, especially low potassium - Mild nausea or abdominal discomfort - Fatigue or weakness

Serious or Rare Side Effects: - Severe dehydration - Significant electrolyte disturbances (hypokalemia, hyponatremia) - Allergic reactions such as rash, angioedema, or anaphylaxis - Acute renal impairment - Gout attacks due to uric acid elevation

Before starting indapamide, several safety considerations should be observed.

Monitor electrolytes: regular blood tests for potassium, sodium, and magnesium levels. Assess renal function: evaluate kidney function prior to therapy. Avoid abrupt discontinuation: taper under medical supervision to prevent rebound hypertension. Use caution in diabetes: monitor blood glucose as diuretics may affect control. Pregnancy and lactation: discuss potential risks with a healthcare provider. Store at room temperature: keep below 25°C in the original pack, protect from moisture.

Indapamide can interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Lithium: increased lithium levels may cause toxicity. - NSAIDs: may diminish diuretic effect and impair renal function. - ACE inhibitors or ARBs: combined use can lead to severe hypotension and electrolyte imbalance.

Moderate Interactions (Monitor Closely): - Antidiabetic agents: may enhance hypoglycemic effect. - Other diuretics: additive diuretic action can cause dehydration. - Corticosteroids: may increase risk of hypokalemia.