Europe — EMA
Indapamide Hemihydrate Crescent Pharma
GNH USA supplies Indapamide Hemihydrate Crescent Pharma (Indapamide), a thiazide-like diuretic for hypertension and edema. Request a quote for global supply.
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What is Indapamide Hemihydrate?
Indapamide, the active ingredient in Indapamide Hemihydrate Crescent Pharma, is a thiazide‑like diuretic presented as a tablet for oral use. It treats hypertension and edema associated with heart failure or renal disease. GNH USA supplies Indapamide Hemihydrate Crescent Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Indapamide Hemihydrate used for?
Indapamide, a thiazide‑like diuretic, is employed to manage conditions related to fluid overload and elevated blood pressure.
Hypertension: lowers systolic and diastolic blood pressure to reduce cardiovascular risk. Edema associated with heart failure: increases urinary excretion to relieve peripheral swelling. Edema associated with renal disease: promotes sodium and water loss to control fluid accumulation.
What are the side effects of Indapamide Hemihydrate?
Indapamide may cause a range of adverse reactions, from mild to serious.
Common Side Effects: - Electrolyte imbalance (e.g., low potassium) - Increased frequency of urination - Dizziness or light‑headedness - Headache - Fatigue - Nausea
Serious or Rare Side Effects: - Severe dehydration - Hyponatremia or severe electrolyte disturbances - Allergic reactions such as rash or angioedema - Blood dyscrasias (e.g., agranulocytosis) - Acute pancreatitis - Hepatic dysfunction
What precautions apply to Indapamide Hemihydrate?
Before initiating therapy, clinicians should consider several safety measures.
Monitor electrolytes: check serum potassium and sodium regularly. Assess renal function: evaluate creatinine clearance prior to use. Evaluate blood pressure: ensure adequate control and avoid excessive hypotension. Use caution in diabetes: monitor glucose as diuresis may affect control. Avoid in severe hepatic impairment: contraindicated due to altered metabolism. Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture.
What does Indapamide Hemihydrate interact with?
Indapamide can interact with several medicines, requiring attention to avoid adverse outcomes.
Major Interactions (Avoid): - Lithium: risk of lithium toxicity due to reduced clearance. - NSAIDs: may blunt diuretic efficacy and affect renal function. - ACE inhibitors/ARBs: can cause excessive potassium loss and hypotension.
Moderate Interactions (Monitor Closely): - Digoxin: increased serum levels may occur. - SSRIs: heightened risk of hyponatremia.
Frequently asked questions
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Product details
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