GNH USA

Europe — EMA

Indapamida Retard Cinfa

GNH USA supplies Indapamida Retard Cinfa (Indapamide), a diuretic for hypertension and edema in heart failure or renal disease. Request a quote for supply.

Indapamide

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What is Indapamide?

Indapamide, the active ingredient in Indapamida Retard Cinfa, is a thiazide‑like diuretic presented as an extended‑release tablet for oral use. It is employed to manage hypertension and to reduce fluid overload in patients with heart‑failure‑related or renal‑disease‑related edema. It is indicated for long‑term blood pressure control and for alleviating peripheral edema, contributing to improved cardiovascular outcomes.

GNH USA supplies Indapamida Retard Cinfa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across markets.

What is Indapamide used for?

Indapamida Retard Cinfa, a thiazide‑like diuretic, is used to treat conditions involving elevated blood pressure or fluid retention.

Hypertension: lowers systolic and diastolic blood pressure, reducing cardiovascular risk. Edema associated with heart failure: enhances urinary sodium and water excretion to decrease pulmonary and peripheral congestion. Edema associated with renal disease: promotes diuresis to manage fluid overload and improve symptom control.

What are the side effects of Indapamide?

Indapamida Retard Cinfa may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Dizziness: sensation of light‑headedness, especially after standing. - Headache: mild to moderate cranial pain. - Fatigue: general tiredness or weakness. - Electrolyte imbalance: low potassium or sodium levels. - Increased uric acid: may precipitate gout attacks. - Gastrointestinal discomfort: nausea or abdominal cramps.

Serious or Rare Side Effects: - Severe dehydration: marked fluid loss requiring medical attention. - Significant electrolyte disturbances: profound hypokalemia or hyponatremia. - Acute renal failure: sudden decline in kidney function. - Allergic reactions: rash, pruritus, or angioedema. - Blood dyscrasias: agranulocytosis or leukopenia. - Photosensitivity: skin reaction to sunlight.

What precautions apply to Indapamide?

When prescribing Indapamida Retard Cinfa, clinicians should observe several safety considerations. - Blood pressure monitoring: check regularly to avoid excessive hypotension. - Electrolyte assessment: monitor potassium and sodium levels during therapy. - Renal function: evaluate creatinine clearance before and during treatment. - Gout history: use cautiously as uric acid may increase. - Drug interactions: review concomitant medications that affect potassium. - Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture.

What does Indapamide interact with?

Indapamida Retard Cinfa can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid): - Lithium: risk of lithium toxicity increased. - NSAIDs: may reduce diuretic efficacy and impair renal function. - ACE inhibitors/ARBs: can cause severe hypotension and renal impairment.

Moderate Interactions (Monitor Closely): - Beta‑blockers: additive blood pressure lowering effect. - Digoxin: may increase risk of arrhythmia due to electrolyte changes. - Antidiabetic agents: may enhance hypoglycemic effect.

Frequently asked questions

What is Indapamida Retard Cinfa used for?+
Indapamida Retard Cinfa contains indapamide, a thiazide‑like diuretic indicated for the treatment of hypertension and for reducing fluid overload in patients with edema due to heart failure or chronic kidney disease.
How does indapamide work in the body?+
Indapamide inhibits the Na⁺/Cl⁻ cotransporter in the distal convoluted tubule, decreasing sodium and chloride reabsorption. This promotes natriuresis and diuresis, lowers extracellular fluid volume, and also causes direct arteriolar vasodilation, together lowering blood pressure.
What determines the dose of Indapamida Retard Cinfa?+
The appropriate dose of Indapamida Retard Cinfa is individualized by the prescribing healthcare professional based on the patient’s clinical condition, blood pressure response, renal function, and electrolyte status. No fixed regimen is provided here.
Is Indapamida Retard Cinfa safe during pregnancy or breastfeeding?+
The pregnancy category for indapamide is not clearly defined. It should only be used during pregnancy or lactation if the potential benefit justifies the potential risk to the fetus or infant, and under close medical supervision.
How do I order Indapamida Retard Cinfa from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Indapamida Retard Cinfa compare with other thiazide diuretics?+
Indapamide shares the core mechanism of thiazide diuretics but has a longer half‑life and additional vasodilatory properties, which can provide more sustained blood‑pressure control and a lower incidence of certain metabolic side effects compared with classic thiazides such as hydrochlorothiazide.
What are the recommended storage conditions for Indapamida Retard Cinfa?+
Store the extended‑release tablets at ambient temperature, preferably below 25 °C. Keep them in the original blister pack, protect from moisture and direct sunlight, and ensure the container is tightly closed.
How is Indapamida Retard Cinfa administered?+
Indapamida Retard Cinfa is taken orally, usually once daily with or without food, as directed by the prescribing clinician. The tablet should be swallowed whole and not split, crushed, or chewed.
What are the most serious risks associated with Indapamida Retard Cinfa?+
Serious risks include severe dehydration, marked electrolyte disturbances such as hypokalemia or hyponatremia, acute renal failure, and rare allergic reactions like angioedema. Patients should be monitored for these events, especially when combined with other diuretics or drugs affecting renal function.
Who should not use Indapamida Retard Cinfa?+
Individuals with known hypersensitivity to indapamide or any component of the formulation should avoid the product. Caution is also advised for patients with severe renal impairment, uncontrolled electrolyte abnormalities, or those taking interacting medications such as lithium or NSAIDs without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Indapamide
Route
Oral Use
Manufacturer
Laboratorios Cinfa S.A.
Origin
EU

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