Imoxat

Imidacloprid/moxidectin, the active ingredient in Imoxat, is an antiparasitic drug presented as a combination formulation for topical or oral use in animals. It targets ectoparasites and endoparasites in companion and livestock species.

GNH USA supplies Imoxat as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Imoxat is used to manage parasitic infestations in animals, covering both external and internal parasite families. - Canine heartworm disease: prevents infection by Dirofilaria immitis in dogs. - Flea infestation in dogs and cats: eliminates adult fleas and reduces egg production. - Intestinal nematodes in dogs: treats common roundworm, hookworm and whipworm infections.

Adverse reactions to Imoxat may vary in frequency and severity.

Common Side Effects: - Mild skin irritation at the application site. - Transient vomiting or nausea. - Diarrhea or soft stools. - Temporary lethargy or reduced activity.

Serious or Rare Side Effects: - Severe allergic reactions, including facial swelling and hives. - Anaphylaxis with respiratory distress. - Neurological signs such as tremors or seizures. - Profound vomiting or hemorrhagic diarrhea.

When using Imoxat, consider the following precautions to ensure safe administration. - Pregnancy: consult a veterinarian before use in breeding animals. - Age: not recommended for puppies or kittens younger than eight weeks. - Concurrent medications: avoid simultaneous use with other ectoparasitic agents without veterinary guidance. - Known hypersensitivity: discontinue use and seek veterinary care if allergic signs appear. - Storage: Store below 25°C: keep in the original container, protect from moisture and light.

Imoxat may interact with other veterinary medicines; monitor the following combinations.

Major Interactions (Avoid): - Co‑administration with other macrocyclic lactones (e.g., ivermectin) can increase neurotoxicity risk. - Use with organophosphate insecticides may potentiate cholinergic toxicity.

Moderate Interactions (Monitor Closely): - Concurrent use with other nicotinic acetylcholine receptor agonists may enhance nervous system side effects. - Combination with corticosteroids may mask early allergic reactions. - Concurrent administration with certain antibiotics (e.g., macrolides) may alter drug metabolism.